Source: MGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ADCK2 Q7Z695 aarF domain containing kinase 2 Kinase 3.6E-07 1
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 13
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 14
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 7
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 2
IFNG P01579 interferon gamma 0.47 0.288 0.962 12
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 2
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 6
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 1
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 10
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 23
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 1
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 6
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 21
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 6
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 1
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 1
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 2
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 3
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 3
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 1
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 4
IL2 P60568 interleukin 2 0.48 0.336 0.885 3