Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ITPR1 Q14643 inositol 1,4,5-trisphosphate receptor type 1 Ion channel 1.00 0.534 0.846 7
PRMT5 O14744 protein arginine methyltransferase 5 Epigenetic regulator 1.00 0.539 0.769 1
DPP10 Q8N608 dipeptidyl peptidase like 10 Enzyme 1.00 0.695 0.577 1
CARM1 Q86X55 coactivator associated arginine methyltransferase 1 Epigenetic regulator 1.00 0.601 0.692 7
PRMT1 Q99873 protein arginine methyltransferase 1 Epigenetic regulator 1.00 0.552 0.808 2
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
STAT6 P42226 signal transducer and activator of transcription 6 Nucleic acid binding 0.99 0.475 0.808 4
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 26
CD86 P42081 CD86 molecule 0.95 0.483 0.769 9
GATA3 P23771 GATA binding protein 3 0.90 0.415 0.846 3
CD40 P25942 CD40 molecule 0.85 0.396 0.846 14
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 45
PDGFB P01127 platelet derived growth factor subunit B Signaling 0.77 0.488 0.846 17
STAT4 Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 0.77 0.471 0.769 6
PIN1 Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.74 0.488 0.769 4
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
RHOA P61586 ras homolog family member A Enzyme modulator 0.60 0.502 0.808 14
SLC18A3 Q16572 solute carrier family 18 member A3 Transporter 0.45 0.608 0.654 3
UCN P55089 urocortin Signaling 0.45 0.539 0.769 6
C5AR1 P21730 complement C5a receptor 1 G-protein coupled receptor 0.40 0.513 0.808 11
PTGER3 P43115 prostaglandin E receptor 3 G-protein coupled receptor 0.37 0.601 0.731 8
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 15
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
DCN P07585 decorin 0.31 0.457 0.808 5