Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885 42
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 42
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
DLG3 Q92796 discs large MAGUK scaffold protein 3 1.00 0.544 0.615 41
GDI1 P31150 GDP dissociation inhibitor 1 Enzyme 0.99 0.572 0.654 41
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 41
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 41
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 40
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 39
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 38
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 38
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 38
CASP9 P55211 caspase 9 Enzyme 7.4E-06 0.458 0.808 37
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 37
IFNG P01579 interferon gamma 0.47 0.288 0.962 36
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 35
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 34
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 34
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885 34
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 34