Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 94
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 60
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 59
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 55
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 49
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 42
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 34
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 32
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 28
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 27
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 26
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 25
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808 22
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 19
BDKRB2 P30411 bradykinin receptor B2 G-protein coupled receptor 0.12 0.585 0.808 17
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846 17
PDGFB P01127 platelet derived growth factor subunit B Signaling 0.77 0.488 0.846 17
CCL11 P51671 C-C motif chemokine ligand 11 Signaling 1.0E-02 0.473 0.885 16