Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 46
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 38
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 28
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 26
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 25
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 25
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 24
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 24
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 23
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 22
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 20
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 18
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885 17
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 17
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 17
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 16
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808 16
NEFL P07196 neurofilament light 0.488 0.769 16
FADD Q13158 Fas associated via death domain 0.53 0.537 0.846 14