Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 60
IFNG P01579 interferon gamma 0.47 0.288 0.962 36
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 32
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 30
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 28
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 26
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846 26
CASP12 Q6UXS9 caspase 12 (gene/pseudogene) 1.3E-04 0.638 0.808 23
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885 22
INS P01308 insulin 0.30 0.445 0.923 18
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808 17
ADRB1 P08588 adrenoceptor beta 1 G-protein coupled receptor 2.9E-06 0.555 0.769 16
CCL11 P51671 C-C motif chemokine ligand 11 Signaling 1.0E-02 0.473 0.885 16
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 16
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846 15
DUSP1 P28562 dual specificity phosphatase 1 1.0E-02 0.491 0.808 13
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885 13
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808 12
PDX1 P52945 pancreatic and duodenal homeobox 1 1.8E-02 0.530 0.654 12
SELL P14151 selectin L 5.0E-07 0.505 0.846 12
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885 11
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846 9
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923 9