Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 340 9
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 285 1
IL6 P05231 interleukin 6 0.32 0.248 0.962 270 4
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 239 0
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 231 5
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 192 93
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 171 2
IFNA2 P01563 interferon alpha 2 0.442 0.885 170 0
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168 2
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 167 4
IFNG P01579 interferon gamma 0.47 0.288 0.962 167 1
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 151 0
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 147 48
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 146 14
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 138 9
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 137 3
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885 136 1
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 130 54
ALB P02768 albumin Transporter 0.64 0.317 0.962 123 9
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 119 12
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 115 30
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 112 15
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 103 4
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 99 10