Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 100 16
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 94 101
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 79 13
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 74 50
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 74 8
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 64 61
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 53 31
LPP Q93052 LIM domain containing preferred translocation partner in lipoma Enzyme modulator 7.2E-03 0.543 0.769 46 45
BACH2 Q9BYV9 BTB domain and CNC homolog 2 1.00 0.539 0.731 41 29
IRF1-AS1 Q8N8D9 IRF1 antisense RNA 1 4.2E-03 0.670 0.385 41 26
ZMIZ1 Q9ULJ6 zinc finger MIZ-type containing 1 1.00 0.588 0.615 40 33
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885 39 22
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846 37 36
THADA Q6YHU6 THADA armadillo repeat containing Receptor 4.6E-41 0.686 0.500 37 33
CDKAL1 Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 1.6E-02 0.617 0.615 33 44
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 33 42
FOXP1 Q9H334 forkhead box P1 1.00 0.460 0.808 33 33
UBE2L3 P68036 ubiquitin conjugating enzyme E2 L3 Enzyme 0.84 0.644 0.615 32 25
CCDC26 Q8TAB7 CCDC26 long non-coding RNA 0.647 0.615 31 41
STAT4 Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 0.77 0.471 0.769 30 28
ANKRD55 Q3KP44 ankyrin repeat domain 55 6.8E-08 0.650 0.462 30 10
RMI2 Q96E14 RecQ mediated genome instability 2 1.9E-02 0.666 0.500 28 19
PNKD Q8N490 PNKD metallo-beta-lactamase domain containing 4.1E-08 0.615 0.615 28 17
PTPN2 P17706 protein tyrosine phosphatase non-receptor type 2 1.00 0.538 0.692 28 17