Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 340 9
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 241 7
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 239 0
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 231 5
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 184 9
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 179 27
IFNA2 P01563 interferon alpha 2 0.442 0.885 170 0
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168 2
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 167 4
IFNG P01579 interferon gamma 0.47 0.288 0.962 167 1
INS P01308 insulin 0.30 0.445 0.923 157 34
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 151 0
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 146 14
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 138 9
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 138 5
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 137 3
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885 136 1
ALB P02768 albumin Transporter 0.64 0.317 0.962 123 9
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 119 12
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 115 1
LEP P41159 leptin 0.46 0.349 0.846 114 3
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 113 9
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 109 3
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885 104 0