Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 101
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 94
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 72
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 71
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 60
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 59
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 42
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 41
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
CXCL1 P09341 C-X-C motif chemokine ligand 1 Signaling 0.12 0.449 0.923 30
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 28
CX3CL1 P78423 C-X3-C motif chemokine ligand 1 Signaling 0.61 0.478 0.808 27
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 26
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 25
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923 24
CXCL2 P19875 C-X-C motif chemokine ligand 2 Signaling 3.6E-07 0.513 0.885 18
ACE2 Q9BYF1 angiotensin I converting enzyme 2 Enzyme 1.00 0.477 0.769 17
BDKRB2 P30411 bradykinin receptor B2 G-protein coupled receptor 0.12 0.585 0.808 17
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 16