Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 49
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 40
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 37
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846 26
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769 21
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 21
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885 14
RXRA P19793 retinoid X receptor alpha Nuclear receptor 1.00 0.543 0.769 13
ATG7 O95352 autophagy related 7 Enzyme 7.4E-12 0.505 0.769 11
FCGR2B P31994 Fc fragment of IgG receptor IIb Cell adhesion 0.46 0.522 0.846 5
LYN P07948 LYN proto-oncogene, Src family tyrosine kinase Kinase 1.00 0.603 0.615 4
PDCD1 Q15116 programmed cell death 1 0.42 0.402 0.846 4
TRAF3IP2 O43734 TRAF3 interacting protein 2 1.6E-09 0.585 0.692 4
ATG5 Q9H1Y0 autophagy related 5 Transporter 0.98 0.462 0.885 3
C1QA P02745 complement C1q A chain 3.8E-03 0.623 0.654 3
JUNB P17275 JunB proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.86 0.467 0.769 3
LBR Q14739 lamin B receptor Enzyme 0.18 0.473 0.808 3
MIR196A2 microRNA 196a-2 0.599 0.577 3
SNRPD1 P62314 small nuclear ribonucleoprotein D1 polypeptide Nucleic acid binding 0.80 0.729 0.615 3
INPP5D Q92835 inositol polyphosphate-5-phosphatase D 0.97 0.558 0.731 2
MAN2A1 Q16706 mannosidase alpha class 2A member 1 1.6E-10 0.705 0.538 2
POLB P06746 DNA polymerase beta Enzyme 3.4E-05 0.606 0.654 2
PTPRC P08575 protein tyrosine phosphatase receptor type C Enzyme 1.00 0.435 0.808 2
RC3H1 Q5TC82 ring finger and CCCH-type domains 1 0.99 0.821 0.154 2