Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 100 16
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 94 101
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 79 13
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 74 50
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 74 8
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 61 54
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 53 31
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 53 30
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 48 44
LPP Q93052 LIM domain containing preferred translocation partner in lipoma Enzyme modulator 7.2E-03 0.543 0.769 46 45
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769 46 41
BACH2 Q9BYV9 BTB domain and CNC homolog 2 1.00 0.539 0.731 41 29
IRF1-AS1 Q8N8D9 IRF1 antisense RNA 1 4.2E-03 0.670 0.385 41 26
MIR4435-2HG MIR4435-2 host gene 0.604 0.692 38 56
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808 38 29
THADA Q6YHU6 THADA armadillo repeat containing Receptor 4.6E-41 0.686 0.500 37 33
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 35 48
CASC15 cancer susceptibility 15 0.603 0.577 35 41
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 34 1
CCDC26 Q8TAB7 CCDC26 long non-coding RNA 0.647 0.615 31 41
HECTD4 Q9Y4D8 HECT domain E3 ubiquitin protein ligase 4 1.00 0.700 0.462 31 11
ZFPM2 Q8WW38 zinc finger protein, FOG family member 2 Transcription factor 1.00 0.565 0.731 30 27
CLEC16A Q2KHT3 C-type lectin domain containing 16A 0.28 0.612 0.654 29 38
RERE Q9P2R6 arginine-glutamic acid dipeptide repeats 1.00 0.526 0.846 29 32