Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 281
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 220
PEX6 Q13608 peroxisomal biogenesis factor 6 6.3E-06 0.547 0.731 212
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 205
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846 200
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing) 0.556 0.808 187
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 160
IFIH1 Q9BYX4 interferon induced with helicase C domain 1 7.0E-44 0.471 0.808 158
PMM2 O15305 phosphomannomutase 2 Enzyme 1.4E-17 0.535 0.769 148
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885 147
ANKRD11 Q6UB99 ankyrin repeat domain 11 1.00 0.556 0.808 145
HUWE1 Q7Z6Z7 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Enzyme 1.00 0.534 0.769 141
BPTF Q12830 bromodomain PHD finger transcription factor 1.00 0.560 0.769 137
NFIX Q14938 nuclear factor I X Nucleic acid binding 1.00 0.547 0.769 137
SON P18583 SON DNA binding protein 1.00 0.565 0.769 132
CDK13 Q14004 cyclin dependent kinase 13 Kinase 0.91 0.606 0.692 119
UBA5 Q9GZZ9 ubiquitin like modifier activating enzyme 5 Enzyme 2.5E-04 0.582 0.731 119
ASXL3 Q9C0F0 ASXL transcriptional regulator 3 1.00 0.590 0.577 118
SLC35A2 P78381 solute carrier family 35 member A2 Transporter 0.72 0.525 0.808 116
COL7A1 Q02388 collagen type VII alpha 1 chain Receptor 2.4E-40 0.545 0.808 113
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692 113
AUTS2 Q8WXX7 activator of transcription and developmental regulator AUTS2 1.00 0.569 0.846 112