BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
45
|
TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
39
|
KRAS |
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
7.9E-04 |
0.320 |
0.923 |
33
|
PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
33
|
HRAS |
P01112
|
HRas proto-oncogene, GTPase
|
Enzyme modulator
|
8.0E-02 |
0.378 |
0.885 |
29
|
EGFR |
P00533
|
epidermal growth factor receptor
|
Kinase
|
0.37 |
0.295 |
0.885 |
28
|
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
27
|
CTNNB1 |
P35222
|
catenin beta 1
|
|
1.00 |
0.303 |
0.885 |
23
|
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
22
|
AKT1 |
P31749
|
AKT serine/threonine kinase 1
|
Kinase
|
0.98 |
0.311 |
0.962 |
20
|
ATM |
Q13315
|
ATM serine/threonine kinase
|
Kinase
|
5.6E-47 |
0.374 |
0.885 |
20
|
ERBB3 |
P21860
|
erb-b2 receptor tyrosine kinase 3
|
Kinase
|
1.7E-15 |
0.448 |
0.808 |
20
|
APC |
P25054
|
APC regulator of WNT signaling pathway
|
|
1.00 |
0.373 |
0.962 |
18
|
NRAS |
P01111
|
NRAS proto-oncogene, GTPase
|
Enzyme modulator
|
0.49 |
0.390 |
0.808 |
17
|
STK11 |
Q15831
|
serine/threonine kinase 11
|
Kinase
|
0.99 |
0.435 |
0.808 |
17
|
ATR |
Q13535
|
ATR serine/threonine kinase
|
Kinase
|
3.5E-09 |
0.456 |
0.923 |
16
|
BRCA2 |
P51587
|
BRCA2 DNA repair associated
|
Nucleic acid binding
|
2.4E-25 |
0.379 |
0.846 |
16
|
KIT |
P10721
|
KIT proto-oncogene, receptor tyrosine kinase
|
Kinase
|
0.98 |
0.366 |
0.808 |
16
|
NOTCH1 |
P46531
|
notch receptor 1
|
|
1.00 |
0.369 |
0.885 |
16
|
AKT2 |
P31751
|
AKT serine/threonine kinase 2
|
Kinase
|
0.64 |
0.474 |
0.769 |
15
|
FGFR2 |
P21802
|
fibroblast growth factor receptor 2
|
Kinase
|
1.00 |
0.380 |
0.808 |
15
|
NOTCH2 |
Q04721
|
notch receptor 2
|
|
1.00 |
0.441 |
0.808 |
15
|
BAP1 |
Q92560
|
BRCA1 associated protein 1
|
Enzyme
|
0.99 |
0.454 |
0.731 |
14
|
BRCA1 |
P38398
|
BRCA1 DNA repair associated
|
Enzyme
|
9.2E-29 |
0.367 |
0.923 |
14
|