Source: MGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
DLG3 Q92796 discs large MAGUK scaffold protein 3 transmembrane receptor regulatory/adaptor protein 1.00 0.575 0.414 42
GDI1 P31150 GDP dissociation inhibitor 1 enzyme modulator; transferase 1.00 0.590 0.448 42
FKRP Q9H9S5 fukutin related protein 6.3E-05 0.514 0.586 38
AUTS2 Q8WXX7 AUTS2, activator of transcription and developmental regulator 1.00 0.590 0.483 28
MBD5 Q9P267 methyl-CpG binding domain protein 5 1.00 0.580 0.552 27
PMM2 O15305 phosphomannomutase 2 isomerase 1.6E-17 0.557 0.621 27
ZBTB18 Q99592 zinc finger and BTB domain containing 18 transcription factor 1.00 0.611 0.345 27
LARGE1 O95461 LARGE xylosyl- and glucuronyltransferase 1 transferase 0.530 0.621 25
FKTN O75072 fukutin 7.7E-07 0.522 0.586 24
MTO1 Q9Y2Z2 mitochondrial tRNA translation optimization 1 6.9E-06 0.636 0.345 24
B4GAT1 O43505 beta-1,4-glucuronyltransferase 1 0.573 0.414 23
LMNA P02545 lamin A/C 1.00 0.406 0.724 20
PTEN P60484 phosphatase and tensin homolog hydrolase; phosphatase 0.82 0.334 0.828 20
ZMPSTE24 O75844 zinc metallopeptidase STE24 hydrolase; protease 1.4E-15 0.527 0.690 20
ARX Q96QS3 aristaless related homeobox 0.91 0.541 0.448 19
CFC1 P0CG37 cripto, FRL-1, cryptic family 1 calcium-binding protein 9.8E-02 0.572 0.552 18
CFC1B P0CG36 cripto, FRL-1, cryptic family 1B calcium-binding protein 0.701 0.103 18
CDKL5 O76039 cyclin dependent kinase like 5 kinase; transferase 1.00 0.551 0.448 17
DAG1 Q14118 dystroglycan 1 receptor 0.97 0.522 0.655 17
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 6.8E-06 0.443 0.759 17
SCN11A Q9UI33 sodium voltage-gated channel alpha subunit 11 transporter 7.3E-24 0.633 0.379 17
TP53 P04637 tumor protein p53 transcription factor 0.17 0.251 0.897 17
TTN Q8WZ42 titin 6.4E-84 0.534 0.655 17
ATR Q13535 ATR serine/threonine kinase kinase; nucleic acid binding; transferase 1.7E-08 0.486 0.759 16