Source: MGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
DLG3 Q92796 discs large MAGUK scaffold protein 3 1.00 0.544 0.615 41
GDI1 P31150 GDP dissociation inhibitor 1 Enzyme 0.99 0.572 0.654 41
CRBN Q96SW2 cereblon Enzyme 2.9E-04 0.551 0.654 33
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 23
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 21
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 21
CFC1 P0CG37 cripto, FRL-1, cryptic family 1 Calcium-binding protein 0.11 0.588 0.577 20
CFC1B P0CG36 cripto, FRL-1, cryptic family 1B 0.700 0.115 20
LMNA P02545 lamin A/C 1.00 0.384 0.885 20
SCN5A Q14524 sodium voltage-gated channel alpha subunit 5 Ion channel 0.91 0.513 0.654 17
ACVR2B Q13705 activin A receptor type 2B Kinase 0.83 0.601 0.615 15
FKRP Q9H9S5 fukutin related protein 9.8E-06 0.513 0.731 15
GHRH P01286 growth hormone releasing hormone Signaling 0.15 0.503 0.769 15
GNRHR P30968 gonadotropin releasing hormone receptor G-protein coupled receptor 6.8E-02 0.540 0.654 15
CSHL1 Q14406 chorionic somatomammotropin hormone like 1 Signaling 3.1E-12 0.647 0.577 14
DNAH5 Q8TE73 dynein axonemal heavy chain 5 Enzyme 4.9E-64 0.590 0.692 14
ECEL1 O95672 endothelin converting enzyme like 1 Enzyme 4.8E-13 0.638 0.308 14
FBN2 P35556 fibrillin 2 Calcium-binding protein 1.00 0.505 0.808 14
GNRH1 P01148 gonadotropin releasing hormone 1 0.15 0.524 0.731 14
KISS1 Q15726 KiSS-1 metastasis suppressor 0.49 0.507 0.808 14
KISS1R Q969F8 KISS1 receptor G-protein coupled receptor 0.44 0.515 0.769 14
LARGE1 O95461 LARGE xylosyl- and glucuronyltransferase 1 Enzyme 0.99 0.526 0.654 14
TACR3 P29371 tachykinin receptor 3 G-protein coupled receptor 1.8E-17 0.553 0.769 14
TNNI2 P48788 troponin I2, fast skeletal type Cellular structure 0.14 0.631 0.423 14