Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.230 None 1.000 0 0 2011 2017
Entrez Id: 355
Gene Symbol: FAS
FAS
Fas cell surface death receptor 0.372 0.923 0.81
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.400 None 0.943 10 0 1978 2020
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1
programmed cell death 1 0.402 0.846 0.42
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.800 None 0.949 3 0 1998 2020
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
cyclin dependent kinase inhibitor 1A 0.403 0.769 1.9E-03
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.240 None 1.000 3 0 1999 2019
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
CD40 ligand 0.414 0.846 0.72
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.300 None 0.980 0 0 1996 2020
Entrez Id: 8678
Gene Symbol: BECN1
BECN1
beclin 1 0.432 0.846 0.94
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.210 None 1.000 0 0 2014 2014
Entrez Id: 5788
Gene Symbol: PTPRC
PTPRC
protein tyrosine phosphatase receptor type C 0.435 0.808 1.00
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.240 None 1.000 1 0 1996 2020
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
cytochrome b-245 beta chain 0.452 0.885 1.00
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.260 None 1.000 1 0 2016 2019
Entrez Id: 2033
Gene Symbol: EP300
EP300
E1A binding protein p300 0.459 0.846 1.00
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.200 None 0 0
Entrez Id: 9474
Gene Symbol: ATG5
ATG5
autophagy related 5 0.462 0.885 0.98
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.390 None 0.944 0 0 2008 2019
Entrez Id: 51284
Gene Symbol: TLR7
TLR7
toll like receptor 7 0.464 0.885 0.98
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.300 None 0.966 0 0 2007 2019
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
JunB proto-oncogene, AP-1 transcription factor subunit 0.467 0.769 0.86
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.230 None 1.000 0 0 2004 2011
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1
interferon induced with helicase C domain 1 0.471 0.808 7.0E-44
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.700 None 1.000 1 0 2006 2019
Entrez Id: 3930
Gene Symbol: LBR
LBR
lamin B receptor 0.473 0.808 0.18
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.220 None 1.000 1 0 1988 2016
Entrez Id: 3716
Gene Symbol: JAK1
JAK1
Janus kinase 1 0.474 0.769 1.00
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.240 None 1.000 1 0 2013 2019
Entrez Id: 1773
Gene Symbol: DNASE1
DNASE1
deoxyribonuclease 1 0.505 0.846 7.0E-21
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.900 None 0.955 1 0 2000 2020
Entrez Id: 10533
Gene Symbol: ATG7
ATG7
autophagy related 7 0.505 0.769 7.4E-12
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.210 None 1.000 0 0 2016 2016
Entrez Id: 2213
Gene Symbol: FCGR2B
FCGR2B
Fc fragment of IgG receptor IIb 0.522 0.846 0.46
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.900 None 0.980 2 0 1995 2019
Entrez Id: 1647
Gene Symbol: GADD45A
GADD45A
growth arrest and DNA damage inducible alpha 0.526 0.769 4.4E-02
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.220 None 1.000 4 0 1999 2019
Entrez Id: 639
Gene Symbol: PRDM1
PRDM1
PR/SET domain 1 0.538 0.731 0.96
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.550 None 1.000 0 0 2009 2017
Entrez Id: 6256
Gene Symbol: RXRA
RXRA
retinoid X receptor alpha 0.543 0.769 1.00
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.200 None 0 0
Entrez Id: 23495
Gene Symbol: TNFRSF13B
TNFRSF13B
TNF receptor superfamily member 13B 0.558 0.769 2.1E-15
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.280 None 1.000 2 0 2001 2019
Entrez Id: 3635
Gene Symbol: INPP5D
INPP5D
inositol polyphosphate-5-phosphatase D 0.558 0.731 0.97
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.210 None 1.000 0 0 2019 2019
Entrez Id: 720
Gene Symbol: C4A
C4A
complement C4A (Rodgers blood group) 0.563 0.769 1.5E-11
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.700 None 0.957 1 0 1987 2018
Entrez Id: 10125
Gene Symbol: RASGRP1
RASGRP1
RAS guanyl releasing protein 1 0.572 0.731 0.97
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.620 None 1.000 1 0 2003 2018