Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.700 0.947 18 0 1986 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.600 1.000 25 0 1996 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.325 0.862 0.50
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.955 47 0 1989 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.350 0.724 9.0E-04
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.937 21 0 1983 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.352 0.862 1.8E-03
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.977 15 0 1986 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.321 0.828 0.38
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.949 11 0 1995 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.298 0.897 2.7E-05
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.925 11 0 1998 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.334 0.828 0.82
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.971 9 0 1998 2017
Entrez Id: 4233
Gene Symbol: MET
MET
MET proto-oncogene, receptor tyrosine kinase 0.405 0.793 0.99
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.944 8 0 1993 2018
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
estrogen receptor 2 0.445 0.828 5.4E-08
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.857 7 0 2002 2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.336 0.931 0.17
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 1.000 7 0 1993 2015
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.382 0.724 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 1.000 5 0 1988 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.417 0.759 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.857 5 0 2000 2011
Entrez Id: 8626
Gene Symbol: TP63
TP63
tumor protein p63 0.419 0.759 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 1.000 5 0 2001 2016
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.365 0.828 0.90
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 1.000 5 0 1990 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2, apoptosis regulator 0.312 0.862 0.57
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.892 5 0 1993 2016
Entrez Id: 6794
Gene Symbol: STK11
STK11
serine/threonine kinase 11 0.467 0.655 0.99
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.968 5 0 1998 2016
Entrez Id: 324
Gene Symbol: APC
APC
APC, WNT signaling pathway regulator 0.397 0.828 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.980 4 0 1993 2016
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.358 0.862 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 1.000 4 0 2002 2016
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Ras association domain family member 1 0.429 0.793 3.7E-06
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.958 4 0 2001 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.263 0.966 0.80
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 1.000 3 0 1991 2009
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.341 0.897 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 1.000 3 0 2002 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.355 0.897 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.885 3 0 1991 2017
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.388 0.828 0.14
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.909 2 0 1998 2014
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
keratin 20 0.448 0.759 1.2E-10
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 0.900 1 0 1993 2015