Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.700 None 0.975 18 0 1986 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.600 None 0.965 25 0 1996 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.971 47 0 1988 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.948 21 0 1983 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.973 15 0 1986 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.941 11 0 1995 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.943 11 0 1996 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.980 9 0 1995 2019
Entrez Id: 4233
Gene Symbol: MET
MET
MET proto-oncogene, receptor tyrosine kinase 0.380 0.846 0.97
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.947 8 0 1993 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 1.000 7 0 1993 2017
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
estrogen receptor 2 0.400 0.923 4.5E-08
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 1.000 7 0 2002 2018
Entrez Id: 8626
Gene Symbol: TP63
TP63
tumor protein p63 0.362 0.769 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.919 5 0 2001 2020
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 1.000 5 0 1988 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.911 5 0 1993 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.969 5 0 1997 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 1.000 5 0 1990 2019
Entrez Id: 6794
Gene Symbol: STK11
STK11
serine/threonine kinase 11 0.435 0.808 0.99
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.962 5 0 1998 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 1.000 4 0 2002 2018
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.982 4 0 1992 2019
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Ras association domain family member 1 0.420 0.808 4.9E-06
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.962 4 0 2001 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 1.000 3 0 1991 2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 1.000 3 0 2002 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.914 3 0 1991 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.929 2 0 1998 2016
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
keratin 20 0.388 0.846 9.1E-11
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
group 0.400 None 0.870 1 0 1993 2020