| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
disease | 0.900 | None | 0.981 | 81 | 0 | 1987 | 2020 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.900 | strong | 0.915 | 8 | 0 | 1998 | 2020 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.700 | None | 0.946 | 61 | 0 | 1991 | 2020 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
disease | 0.700 | None | 0.971 | 49 | 0 | 1990 | 2020 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.700 | None | 0.990 | 35 | 0 | 1988 | 2020 | ||||||||
|
glycogen synthase kinase 3 beta | 0.430 | 0.846 | 0.96 |
|
disease | 0.700 | None | 0.982 | 4 | 0 | 2000 | 2020 | ||||||||
|
homeostatic iron regulator | 0.436 | 0.846 | 2.6E-08 |
|
disease | 0.700 | strong | 0.963 | 3 | 0 | 2001 | 2018 | ||||||||
|
ADAM metallopeptidase domain 10 | 0.489 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.986 | 2 | 0 | 2000 | 2019 | ||||||||
|
triggering receptor expressed on myeloid cells 2 | 0.519 | 0.769 | 3.3E-09 |
|
disease | 0.700 | limited | 0.977 | 1 | 0 | 2007 | 2020 | ||||||||
|
plasminogen activator, urokinase | 0.425 | 0.923 | 2.3E-06 |
|
disease | 0.680 | None | 1.000 | 4 | 0 | 2002 | 2013 | ||||||||
|
beta-secretase 1 | 0.559 | 0.769 | 0.88 |
|
disease | 0.600 | None | 0.985 | 25 | 0 | 1999 | 2020 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.600 | None | 0.966 | 5 | 0 | 1989 | 2020 | ||||||||
|
insulin degrading enzyme | 0.604 | 0.577 | 6.6E-03 |
|
disease | 0.600 | None | 0.955 | 3 | 0 | 2000 | 2019 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.600 | None | 0.958 | 2 | 0 | 1991 | 2020 | ||||||||
|
caspase 3 | 0.351 | 0.923 | 0.10 |
|
disease | 0.600 | None | 0.980 | 2 | 0 | 1999 | 2020 | ||||||||
|
ATP synthase F1 subunit alpha | 0.604 | 0.731 | 1.00 |
|
disease | 0.540 | None | 1.000 | 1 | 0 | 2003 | 2017 | ||||||||
|
insulin | 0.445 | 0.923 | 0.30 |
|
disease | 0.530 | None | 1.000 | 1 | 0 | 1991 | 2020 | ||||||||
|
sortilin related receptor 1 | 0.582 | 0.692 | 7.7E-11 |
|
disease | 0.500 | None | 0.973 | 11 | 0 | 2004 | 2020 | ||||||||
|
presenilin 2 | 0.550 | 0.654 | 5.4E-04 |
|
disease | 0.500 | None | 0.977 | 10 | 0 | 1995 | 2020 | ||||||||
|
alpha-2-macroglobulin | 0.529 | 0.769 | 4.5E-11 |
|
disease | 0.500 | None | 0.769 | 4 | 0 | 1998 | 2018 | ||||||||
|
apolipoprotein C1 | 0.581 | 0.577 | 0.22 |
|
disease | 0.500 | None | 1.000 | 2 | 0 | 1999 | 2019 | ||||||||
|
myeloperoxidase | 0.377 | 0.923 | 7.1E-15 |
|
disease | 0.500 | None | 1.000 | 1 | 0 | 1999 | 2019 | ||||||||
|
clusterin | 0.426 | 0.885 | 7.8E-05 |
|
disease | 0.500 | None | 0.940 | 1 | 0 | 1991 | 2020 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.500 | None | 0.900 | 1 | 0 | 1999 | 2018 | ||||||||
|
visinin like 1 | 0.631 | 0.423 | 0.46 |
|
disease | 0.490 | None | 1.000 | 1 | 0 | 2001 | 2019 |