Source: RGD

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7038
Gene Symbol: TG
TG
thyroglobulin 0.480 0.808 2.9E-59
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.400 None 1.000 1 0 1986 2020
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.310 None 1.000 1 0 1982 2003
Entrez Id: 6469
Gene Symbol: SHH
SHH
sonic hedgehog signaling molecule 0.461 0.846 0.98
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.300 None 1.000 1 0 2008 2008
Entrez Id: 7200
Gene Symbol: TRH
TRH
thyrotropin releasing hormone 0.519 0.846 8.9E-04
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.290 None 1.000 1 0 1978 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.270 None 1.000 1 0 1992 2019
Entrez Id: 9572
Gene Symbol: NR1D1
NR1D1
nuclear receptor subfamily 1 group D member 1 0.608 0.692 0.82
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.230 None 1.000 1 0 1992 2019
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 0.529 0.808 1.00
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.220 None 1.000 1 0 1999 2015
Entrez Id: 9611
Gene Symbol: NCOR1
NCOR1
nuclear receptor corepressor 1 0.597 0.731 1.00
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.220 None 1.000 1 0 2000 2017
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.345 0.923 0.66
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.220 None 1.000 1 0 2010 2018
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
superoxide dismutase 1 0.379 0.962 0.18
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 2 0 2003 2012
Entrez Id: 3586
Gene Symbol: IL10
IL10
interleukin 10 0.281 0.923 5.9E-03
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 0.500 1 0 2014 2019
Entrez Id: 6906
Gene Symbol: SERPINA7
SERPINA7
serpin family A member 7 0.641 0.615 2.6E-03
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 1990 1990
Entrez Id: 4684
Gene Symbol: NCAM1
NCAM1
neural cell adhesion molecule 1 0.415 0.885 1.00
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2010 2010
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
proliferating cell nuclear antigen 0.382 0.846 0.98
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2011 2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
nitric oxide synthase 3 0.378 0.885 6.7E-07
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 1997 2018
Entrez Id: 7351
Gene Symbol: UCP2
UCP2
uncoupling protein 2 0.493 0.808 1.5E-10
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2010 2010
Entrez Id: 7352
Gene Symbol: UCP3
UCP3
uncoupling protein 3 0.619 0.577 9.6E-10
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2007 2007
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3
patatin like phospholipase domain containing 3 0.556 0.692 5.7E-08
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2009 2009
Entrez Id: 210
Gene Symbol: ALAD
ALAD
aminolevulinate dehydratase 0.556 0.615 5.6E-05
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2007 2007
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
adrenoceptor beta 2 0.442 0.923 0.53
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 1991 2007
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
cytochrome P450 family 19 subfamily A member 1 0.410 0.885 1.7E-05
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2010 2018
Entrez Id: 1641
Gene Symbol: DCX
DCX
doublecortin 0.511 0.769 0.30
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 2012 2018
Entrez Id: 9868
Gene Symbol: TOMM70
TOMM70
translocase of outer mitochondrial membrane 70 0.805 0.308 1.00
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.210 None 1.000 1 0 1999 1999
Entrez Id: 4625
Gene Symbol: MYH7
MYH7
myosin heavy chain 7 0.516 0.692 4.2E-16
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.200 None 1.000 2 0 1987 1991
Entrez Id: 5122
Gene Symbol: PCSK1
PCSK1
proprotein convertase subtilisin/kexin type 1 0.548 0.615 2.7E-09
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.200 None 1.000 2 0 2004 2007