| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
cadherin 1 | 0.401 | 0.808 | 0.15 |
|
disease | 0.800 | None | 0.933 | 6 | 0 | 1996 | 2020 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.700 | None | 0.963 | 3 | 0 | 1988 | 2020 | ||||||||
|
MET proto-oncogene, receptor tyrosine kinase | 0.380 | 0.846 | 0.97 |
|
disease | 0.700 | None | 0.983 | 2 | 0 | 1992 | 2019 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
disease | 0.700 | None | 0.957 | 2 | 0 | 1996 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.700 | None | 0.992 | 1 | 0 | 2005 | 2020 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.700 | None | 0.950 | 0 | 0 | 1992 | 2019 | ||||||||
|
interferon regulatory factor 1 | 0.468 | 0.769 | 0.99 |
|
disease | 0.660 | None | 1.000 | 0 | 0 | 1998 | 2019 | ||||||||
|
Kruppel like factor 6 | 0.501 | 0.846 | 0.98 |
|
disease | 0.660 | None | 1.000 | 0 | 0 | 2005 | 2019 | ||||||||
|
mutY DNA glycosylase | 0.521 | 0.769 | 1.3E-18 |
|
disease | 0.640 | None | 1.000 | 0 | 0 | 2004 | 2011 | ||||||||
|
caspase 10 | 0.528 | 0.692 | 4.6E-12 |
|
disease | 0.610 | None | 1.000 | 0 | 0 | 2002 | 2002 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.600 | None | 1.000 | 1 | 0 | 1998 | 2019 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.500 | None | 0.907 | 3 | 0 | 2000 | 2018 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.500 | None | 1.000 | 2 | 0 | 1987 | 2019 | ||||||||
|
protein kinase AMP-activated catalytic subunit alpha 1 | 0.453 | 0.846 | 0.14 |
|
disease | 0.500 | None | 0.944 | 1 | 0 | 2011 | 2019 | ||||||||
|
interleukin 1 receptor antagonist | 0.373 | 0.923 | 3.1E-02 |
|
disease | 0.500 | None | 0.833 | 0 | 0 | 2003 | 2018 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.460 | None | 0.857 | 1 | 0 | 2000 | 2018 | ||||||||
|
zinc finger and BTB domain containing 20 | 0.566 | 0.731 | 0.97 |
|
disease | 0.430 | None | 1.000 | 1 | 0 | 2011 | 2019 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.400 | None | 0.979 | 4 | 0 | 1998 | 2020 | ||||||||
|
thymidylate synthetase | 0.425 | 0.846 | 0.72 |
|
disease | 0.400 | None | 0.938 | 4 | 0 | 1992 | 2019 | ||||||||
|
dihydropyrimidine dehydrogenase | 0.493 | 0.846 | 3.4E-22 |
|
disease | 0.400 | None | 1.000 | 3 | 0 | 2000 | 2017 | ||||||||
|
AT-rich interaction domain 1A | 0.455 | 0.846 | 1.00 |
|
disease | 0.400 | None | 1.000 | 3 | 0 | 2011 | 2020 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 0.989 | 3 | 0 | 1986 | 2019 | ||||||||
|
DNA methyltransferase 1 | 0.406 | 0.885 | 1.00 |
|
disease | 0.400 | None | 0.850 | 2 | 0 | 2001 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.400 | None | 0.975 | 2 | 0 | 1991 | 2020 | ||||||||
|
prostate stem cell antigen | 0.555 | 0.615 | 0.17 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 2008 | 2019 |