Source: CGI

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 1.000 None 0.983 0 0 1986 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0025202
Disease: melanoma
melanoma
disease 0.800 strong 0.950 0 0 1994 2020
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
HRas proto-oncogene, GTPase 0.378 0.885 8.0E-02
CUI: C0025202
Disease: melanoma
melanoma
disease 0.800 None 1.000 0 0 1984 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0025202
Disease: melanoma
melanoma
disease 0.800 strong 0.950 0 0 1997 2020
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
cyclin dependent kinase 4 0.412 0.808 6.3E-02
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 strong 0.961 0 0 1994 2020
Entrez Id: 2776
Gene Symbol: GNAQ
GNAQ
G protein subunit alpha q 0.516 0.808 0.98
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 None 0.967 0 0 1989 2019
Entrez Id: 4286
Gene Symbol: MITF
MITF
melanocyte inducing transcription factor 0.499 0.808 0.98
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 None 0.974 0 0 2002 2020
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 None 0.969 0 0 1987 2020
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
mitogen-activated protein kinase kinase 1 0.439 0.846 0.90
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 None 1.000 0 0 2003 2019
Entrez Id: 6794
Gene Symbol: STK11
STK11
serine/threonine kinase 11 0.435 0.808 0.99
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 None 1.000 0 0 1999 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 None 0.943 0 0 1991 2020
Entrez Id: 2767
Gene Symbol: GNA11
GNA11
G protein subunit alpha 11 0.563 0.731 0.89
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 None 1.000 0 0 1989 2019
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
BRCA1 associated protein 1 0.454 0.731 0.99
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 strong 0.950 0 0 2010 2019
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
erb-b2 receptor tyrosine kinase 4 0.455 0.846 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 None 0.917 0 0 2009 2018
Entrez Id: 5605
Gene Symbol: MAP2K2
MAP2K2
mitogen-activated protein kinase kinase 2 0.534 0.731 0.97
CUI: C0025202
Disease: melanoma
melanoma
disease 0.670 None 1.000 0 0 2011 2019
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
Rac family small GTPase 1 0.429 0.962 0.76
CUI: C0025202
Disease: melanoma
melanoma
disease 0.600 None 1.000 0 0 2004 2019
Entrez Id: 4763
Gene Symbol: NF1
NF1
neurofibromin 1 0.440 0.885 0.90
CUI: C0025202
Disease: melanoma
melanoma
disease 0.600 None 1.000 0 0 1993 2018
Entrez Id: 5537
Gene Symbol: PPP6C
PPP6C
protein phosphatase 6 catalytic subunit 0.729 0.231 0.86
CUI: C0025202
Disease: melanoma
melanoma
disease 0.540 None 1.000 0 0 2012 2015
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 None 0.986 0 0 1996 2020
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
Raf-1 proto-oncogene, serine/threonine kinase 0.418 0.885 0.85
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 None 1.000 0 0 2002 2019
Entrez Id: 7508
Gene Symbol: XPC
XPC
XPC complex subunit, DNA damage recognition and repair factor 0.504 0.808 3.7E-11
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 None 0.909 0 0 2005 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 None 0.965 0 0 2005 2019
Entrez Id: 8295
Gene Symbol: TRRAP
TRRAP
transformation/transcription domain associated protein 0.572 0.692 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 None 1.000 0 0 2011 2011
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit 0.420 0.846 7.1E-20
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 None 0.938 0 0 2001 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 None 0.976 0 0 2002 2020