| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
synuclein alpha | 0.427 | 0.885 | 0.88 |
|
disease | 0.700 | None | 0.983 | 64 | 0 | 1997 | 2020 | ||||||||
|
parkin RBR E3 ubiquitin protein ligase | 0.431 | 0.846 | 6.9E-07 |
|
disease | 0.600 | None | 0.974 | 32 | 0 | 1998 | 2020 | ||||||||
|
PTEN induced kinase 1 | 0.516 | 0.769 | 1.9E-10 |
|
disease | 0.600 | None | 0.987 | 20 | 0 | 2002 | 2020 | ||||||||
|
Parkinsonism associated deglycase | 0.535 | 0.808 | 0.75 |
|
disease | 0.600 | None | 0.973 | 17 | 0 | 2003 | 2020 | ||||||||
|
monoamine oxidase B | 0.533 | 0.808 | 1.00 |
|
disease | 0.600 | None | 0.991 | 3 | 0 | 1993 | 2020 | ||||||||
|
solute carrier family 18 member A2 | 0.554 | 0.769 | 7.6E-02 |
|
disease | 0.600 | None | 0.966 | 3 | 0 | 1996 | 2020 | ||||||||
|
tyrosine hydroxylase | 0.462 | 0.885 | 1.7E-06 |
|
disease | 0.600 | None | 0.979 | 2 | 0 | 1989 | 2020 | ||||||||
|
ATPase cation transporting 13A2 | 0.566 | 0.577 | 9.0E-09 |
|
disease | 0.600 | strong | 0.946 | 2 | 0 | 2007 | 2019 | ||||||||
|
leucine rich repeat kinase 2 | 0.510 | 0.808 | 2.6E-30 |
|
disease | 0.500 | None | 0.983 | 71 | 0 | 2002 | 2020 | ||||||||
|
glucosylceramidase beta | 0.500 | 0.808 | 1.4E-06 |
|
disease | 0.500 | None | 0.989 | 8 | 0 | 2004 | 2020 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.500 | None | 0.972 | 6 | 0 | 1999 | 2019 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.400 | None | 0.906 | 5 | 0 | 1995 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.980 | 4 | 0 | 1999 | 2020 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.400 | None | 0.900 | 3 | 0 | 2002 | 2018 | ||||||||
|
ceruloplasmin | 0.466 | 0.846 | 4.2E-10 |
|
disease | 0.400 | None | 0.938 | 3 | 0 | 2004 | 2020 | ||||||||
|
solute carrier family 6 member 3 | 0.453 | 0.885 | 1.00 |
|
disease | 0.400 | None | 0.935 | 3 | 0 | 1994 | 2020 | ||||||||
|
glutathione S-transferase mu 1 | 0.380 | 0.923 | 2.1E-03 |
|
disease | 0.400 | None | 0.750 | 2 | 0 | 1999 | 2019 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 2004 | 2019 | ||||||||
|
superoxide dismutase 1 | 0.379 | 0.962 | 0.18 |
|
disease | 0.400 | None | 0.971 | 2 | 0 | 1993 | 2020 | ||||||||
|
heat shock protein family A (Hsp70) member 9 | 0.502 | 0.885 | 0.97 |
|
disease | 0.400 | None | 0.818 | 1 | 0 | 2006 | 2018 | ||||||||
|
homeostatic iron regulator | 0.436 | 0.846 | 2.6E-08 |
|
disease | 0.400 | None | 0.727 | 1 | 0 | 2002 | 2018 | ||||||||
|
heme oxygenase 1 | 0.381 | 0.923 | 9.7E-03 |
|
disease | 0.400 | None | 0.905 | 1 | 0 | 1997 | 2020 | ||||||||
|
mitogen-activated protein kinase kinase kinase 5 | 0.513 | 0.808 | 0.52 |
|
disease | 0.360 | None | 0.833 | 1 | 0 | 2006 | 2020 | ||||||||
|
NAD(P)H quinone dehydrogenase 1 | 0.434 | 0.885 | 1.2E-09 |
|
disease | 0.340 | None | 1.000 | 1 | 0 | 2001 | 2019 | ||||||||
|
insulin like growth factor 2 | 0.390 | 0.885 | 4.4E-02 |
|
disease | 0.330 | None | 1.000 | 1 | 0 | 2008 | 2017 |