Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3952
Gene Symbol: LEP
LEP
leptin 0.400 0.793 0.39
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.600 0.932 15 0 1976 2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
nitric oxide synthase 3 0.401 0.862 8.9E-07
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.600 1.000 2 0 2003 2018
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.432 0.828 8.2E-02
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.580 1.000 2 0 2009 2017
Entrez Id: 3606
Gene Symbol: IL18
IL18
interleukin 18 0.404 0.862 2.9E-02
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.530 1.000 2 0 2006 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.263 0.966 0.80
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.300 0.857 1 0 2000 2016
Entrez Id: 948
Gene Symbol: CD36
CD36
CD36 molecule 0.505 0.828 6.6E-61
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.300 0.909 1 0 1999 2013
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
serpin family E member 1 0.384 0.793 4.7E-02
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.300 1.000 1 0 1997 2016
Entrez Id: 335
Gene Symbol: APOA1
APOA1
apolipoprotein A1 0.463 0.759 5.5E-04
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.300 1.000 1 0 2003 2016
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.388 0.828 0.14
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.300 0.900 1 0 2002 2018
Entrez Id: 3290
Gene Symbol: HSD11B1
HSD11B1
hydroxysteroid 11-beta dehydrogenase 1 0.577 0.655 0.41
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.300 1.000 1 0 2004 2018
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
insulin receptor substrate 1 0.532 0.621 3.5E-02
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.290 1.000 1 0 2000 2015
Entrez Id: 345
Gene Symbol: APOC3
APOC3
apolipoprotein C3 0.552 0.586 9.4E-03
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.290 1.000 1 0 2004 2016
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.406 0.862 3.9E-08
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.250 1.000 1 0 2001 2015
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
insulin like growth factor 2 0.399 0.828 4.7E-02
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.240 1.000 1 0 2002 2015
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
PPARG coactivator 1 alpha 0.497 0.828 1.00
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.240 1.000 1 0 2005 2013
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
heme oxygenase 1 0.403 0.862 7.9E-03
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.220 1.000 1 0 2012 2016
Entrez Id: 9365
Gene Symbol: KL
KL
klotho 0.495 0.621 2.2E-04
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.220 1.000 1 0 2000 2016
Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
phospholipase A2 group VII 0.584 0.552 8.9E-22
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.220 1.000 1 0 2007 2015
Entrez Id: 2053
Gene Symbol: EPHX2
EPHX2
epoxide hydrolase 2 0.633 0.448 1.4E-21
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.210 1.000 1 0 2012 2015
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase 0.584 0.621 1.00
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.210 1.000 1 0 2009 2012
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.210 < 0.001 1 0 2007 2012
Entrez Id: 94241
Gene Symbol: TP53INP1
TP53INP1
tumor protein p53 inducible nuclear protein 1 0.672 0.345 4.8E-04
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.200 2 0 2007 2015
Entrez Id: 2539
Gene Symbol: G6PD
G6PD
glucose-6-phosphate dehydrogenase 0.476 0.724 0.94
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.200 2 0 2009 2015
Entrez Id: 10135
Gene Symbol: NAMPT
NAMPT
nicotinamide phosphoribosyltransferase 0.564 0.690 0.98
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.200 1 0 2005 2005
Entrez Id: 9965
Gene Symbol: FGF19
FGF19
fibroblast growth factor 19 0.630 0.379 0.57
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
disease 0.200 1 0 2017 2017