Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 177
Gene Symbol: AGER
AGER
CUI: C0004096
Disease: Asthma
Asthma
0.290 ModifyingMutation RGD Proteomic analysis reveals the deregulation of inflammation-related proteins in acupuncture-treated rats with asthma onset. 23304218

2012

Entrez Id: 177
Gene Symbol: AGER
AGER
CUI: C0004096
Disease: Asthma
Asthma
0.290 Therapeutic RGD Proteomic analysis reveals the deregulation of inflammation-related proteins in acupuncture-treated rats with asthma onset. 23304218

2012

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0004096
Disease: Asthma
Asthma
0.210 Biomarker RGD AGTR1 expression is potentially associated with airway remodeling and dysfunction in asthma. 19080339

2008

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0004096
Disease: Asthma
Asthma
0.210 Biomarker RGD Effect of valsartan on the expression of angiotensin II receptors in the lung of chronic antigen exposure rats. 19080339

2008

Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0004096
Disease: Asthma
Asthma
0.200 Biomarker RGD Airway hyperresponsiveness to bradykinin induced by allergen challenge in actively sensitised Brown Norway rats. 14727005

2004

Entrez Id: 719
Gene Symbol: C3AR1
C3AR1
CUI: C0004096
Disease: Asthma
Asthma
0.250 Biomarker RGD Use of monoclonal antibodies to assess expression of anaphylatoxin receptors in rat and murine models of lung inflammation. 17544263

2007

Entrez Id: 727
Gene Symbol: C5
C5
CUI: C0004096
Disease: Asthma
Asthma
0.230 Biomarker RGD Contribution of anaphylatoxin C5a to late airway responses after repeated exposure of antigen to allergic rats. 11591795

2001

Entrez Id: 728
Gene Symbol: C5AR1
C5AR1
CUI: C0004096
Disease: Asthma
Asthma
0.270 Biomarker RGD Use of monoclonal antibodies to assess expression of anaphylatoxin receptors in rat and murine models of lung inflammation. 17544263

2007

Entrez Id: 10498
Gene Symbol: CARM1
CARM1
CUI: C0004096
Disease: Asthma
Asthma
0.200 Biomarker RGD In the lung tissue of the asthmatic rats, the gene expressions of PRMT1 (P<0.01), PRMT2 (P<0.01), PRMT3 (P<0.05) and PRMT5 (P<0.05) were significantly increased, but the expression of PRMT4 gene (P<0.05) was significantly decreased as compared with those in the control tissue. 20423833

2010

Entrez Id: 6356
Gene Symbol: CCL11
CCL11
CUI: C0004096
Disease: Asthma
Asthma
0.700 Therapeutic RGD Twenty-four hours after asthma was induced, lung histomorphological changes, cells in bronchoalveolar lavage fluid (BALF), contents of eotaxin, MCP-1, and IL-8 in BALF, and the expression of IFN-γ and IL-4 mRNAs were observed. 22932891

2012

Entrez Id: 6356
Gene Symbol: CCL11
CCL11
CUI: C0004096
Disease: Asthma
Asthma
0.700 Biomarker RGD [The roles of interleukin-5 and eotaxin in signal transmission between lung and bone marrow of rat asthmatic models]. 17074272

2006

Entrez Id: 6361
Gene Symbol: CCL17
CCL17
CUI: C0004096
Disease: Asthma
Asthma
0.300 Biomarker RGD In contrast to the findings in the asthma and lung fibrosis models, the increased expression of MDC and TARC in the cigarette-smoke model was not associated with an increased infiltration of Th2 cells into smoke-treated lungs. 15993846

2005

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0004096
Disease: Asthma
Asthma
0.600 Biomarker RGD Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): impact of vehicle for topical induction. 17964702

2008

Entrez Id: 6367
Gene Symbol: CCL22
CCL22
CUI: C0004096
Disease: Asthma
Asthma
0.270 Biomarker RGD In contrast to the findings in the asthma and lung fibrosis models, the increased expression of MDC and TARC in the cigarette-smoke model was not associated with an increased infiltration of Th2 cells into smoke-treated lungs. 15993846

2005

Entrez Id: 10344
Gene Symbol: CCL26
CCL26
CUI: C0004096
Disease: Asthma
Asthma
0.300 Therapeutic RGD AcCystatin, an immunoregulatory molecule from Angiostrongylus cantonensis, ameliorates the asthmatic response in an aluminium hydroxide/ovalbumin-induced rat model of asthma. 25399816

2015

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0004096
Disease: Asthma
Asthma
0.600 Biomarker RGD Role of the extracellular signal-regulated kinase 1/2 signaling pathway in regulating the secretion of bronchial smooth muscle cells in a rat model of chronic asthma. 18208670

2008

Entrez Id: 1232
Gene Symbol: CCR3
CCR3
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker RGD Topical inhibition of CCR3 expression, using an AS-ODN, could represent a novel approach for the treatment of asthma. 16978084

2006

Entrez Id: 1233
Gene Symbol: CCR4
CCR4
CUI: C0004096
Disease: Asthma
Asthma
0.280 Biomarker RGD Elevated expression of TARC (CCL17) and MDC (CCL22) in models of cigarette smoke-induced pulmonary inflammation. 15993846

2005

Entrez Id: 1237
Gene Symbol: CCR8
CCR8
CUI: C0004096
Disease: Asthma
Asthma
0.210 Biomarker RGD Elevated expression of TARC (CCL17) and MDC (CCL22) in models of cigarette smoke-induced pulmonary inflammation. 15993846

2005

Entrez Id: 958
Gene Symbol: CD40
CD40
CUI: C0004096
Disease: Asthma
Asthma
0.250 Therapeutic RGD Leukocyte infiltration and activation of the CD40-CD40 ligand costimulatory pathway may promote inflammatory processes such as asthma. 20205594

2010

Entrez Id: 942
Gene Symbol: CD86
CD86
CUI: C0004096
Disease: Asthma
Asthma
0.230 Biomarker RGD Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma control. 20668438

2011

Entrez Id: 1103
Gene Symbol: CHAT
CHAT
CUI: C0004096
Disease: Asthma
Asthma
0.200 Biomarker RGD Down-regulation of the non-neuronal acetylcholine synthesis and release machinery in acute allergic airway inflammation of rat and mouse. 17328924

2007

Entrez Id: 1439
Gene Symbol: CSF2RB
CSF2RB
CUI: C0004096
Disease: Asthma
Asthma
0.200 Biomarker RGD Multitargeted approach using antisense oligonucleotides for the treatment of asthma. 17145927

2006

Entrez Id: 1634
Gene Symbol: DCN
DCN
CUI: C0004096
Disease: Asthma
Asthma
0.200 Biomarker RGD Airway remodeling in allergen-challenged Brown Norway rats: distribution of proteoglycans. 16387756

2006

Entrez Id: 57628
Gene Symbol: DPP10
DPP10
CUI: C0004096
Disease: Asthma
Asthma
0.300 Biomarker RGD Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats. 17967935

2008