| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 1.000 | strong | 0.951 | 24 | 69 | 1994 | 2020 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 1.000 | strong | 0.956 | 22 | 88 | 1992 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 1.000 | None | 0.985 | 1 | 6 | 2001 | 2020 | ||||||||
|
BRCA1 associated RING domain 1 | 0.597 | 0.538 | 1.4E-24 |
|
disease | 1.000 | limited | 0.896 | 0 | 1 | 1996 | 2020 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 1.000 | None | 0.967 | 0 | 1 | 1983 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 1.000 | None | 0.973 | 0 | 0 | 1982 | 2020 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.800 | None | 0.970 | 3 | 1 | 2006 | 2020 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.800 | None | 0.963 | 3 | 1 | 2001 | 2019 | ||||||||
|
BRCA1 interacting protein C-terminal helicase 1 | 0.507 | 0.731 | 6.2E-17 |
|
disease | 0.800 | None | 0.951 | 2 | 2 | 2001 | 2020 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.800 | strong | 0.956 | 0 | 0 | 1997 | 2020 | ||||||||
|
cadherin 1 | 0.401 | 0.808 | 0.15 |
|
disease | 0.800 | limited | 1.000 | 0 | 2 | 1991 | 2019 | ||||||||
|
caveolin 1 | 0.388 | 0.885 | 8.3E-03 |
|
disease | 0.800 | None | 0.977 | 0 | 1 | 1999 | 2019 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.700 | limited | 0.993 | 1 | 1 | 1999 | 2020 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
disease | 0.700 | None | 0.942 | 0 | 0 | 1991 | 2020 | ||||||||
|
E1A binding protein p300 | 0.459 | 0.846 | 1.00 |
|
disease | 0.700 | None | 1.000 | 0 | 1 | 2004 | 2020 | ||||||||
|
RAD54 like | 0.633 | 0.423 | 2.4E-15 |
|
disease | 0.620 | None | 0.500 | 0 | 1 | 2017 | 2017 | ||||||||
|
RAD51 recombinase | 0.447 | 0.846 | 2.7E-02 |
|
disease | 0.600 | None | 0.957 | 2 | 1 | 1997 | 2019 | ||||||||
|
F-box and WD repeat domain containing 7 | 0.465 | 0.808 | 1.00 |
|
disease | 0.600 | None | 1.000 | 0 | 1 | 2001 | 2019 | ||||||||
|
GATA binding protein 3 | 0.415 | 0.846 | 0.90 |
|
disease | 0.600 | None | 0.950 | 0 | 0 | 1999 | 2020 | ||||||||
|
prohibitin | 0.511 | 0.846 | 0.76 |
|
disease | 0.600 | None | 0.944 | 0 | 2 | 1994 | 2018 | ||||||||
|
receptor tyrosine kinase like orphan receptor 1 | 0.552 | 0.731 | 1.00 |
|
disease | 0.600 | None | 1.000 | 0 | 1 | 2012 | 2020 | ||||||||
|
fibronectin 1 | 0.365 | 0.962 | 1.4E-03 |
|
disease | 0.600 | None | 1.000 | 0 | 1 | 1997 | 2020 | ||||||||
|
androgen receptor | 0.351 | 0.846 | 0.99 |
|
disease | 0.600 | None | 0.947 | 0 | 2 | 1990 | 2020 | ||||||||
|
nitric oxide synthase 2 | 0.364 | 0.923 | 4.0E-15 |
|
disease | 0.600 | None | 1.000 | 0 | 1 | 1998 | 2017 | ||||||||
|
parathyroid hormone like hormone | 0.453 | 0.846 | 0.81 |
|
disease | 0.600 | None | 0.982 | 0 | 0 | 1992 | 2019 |