| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.700 | None | 0.976 | 4060 | 54 | 1989 | 2020 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.700 | None | 0.979 | 529 | 12 | 1989 | 2020 | ||||||||
|
ALK receptor tyrosine kinase | 0.396 | 0.846 | 3.2E-06 |
|
disease | 0.600 | None | 0.990 | 1046 | 11 | 2007 | 2020 | ||||||||
|
MET proto-oncogene, receptor tyrosine kinase | 0.380 | 0.846 | 0.97 |
|
disease | 0.600 | None | 0.986 | 216 | 7 | 2002 | 2020 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.600 | None | 0.957 | 116 | 3 | 1994 | 2020 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
disease | 0.600 | None | 0.962 | 53 | 0 | 2006 | 2020 | ||||||||
|
checkpoint with forkhead and ring finger domains | 0.633 | 0.500 | 7.9E-04 |
|
disease | 0.550 | None | 0.800 | 5 | 1 | 2008 | 2015 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.500 | None | 0.990 | 191 | 7 | 2003 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.500 | None | 0.974 | 154 | 11 | 1989 | 2020 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.500 | None | 1.000 | 127 | 17 | 2002 | 2020 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.500 | None | 1.000 | 120 | 2 | 1998 | 2020 | ||||||||
|
serine/threonine kinase 11 | 0.435 | 0.808 | 0.99 |
|
disease | 0.500 | None | 0.985 | 68 | 2 | 2006 | 2020 | ||||||||
|
mitogen-activated protein kinase kinase 1 | 0.439 | 0.846 | 0.90 |
|
disease | 0.500 | None | 1.000 | 19 | 3 | 1995 | 2019 | ||||||||
|
caspase 8 | 0.404 | 0.923 | 3.7E-06 |
|
disease | 0.500 | None | 1.000 | 16 | 1 | 2007 | 2019 | ||||||||
|
CLPTM1 like | 0.551 | 0.654 | 4.4E-05 |
|
disease | 0.470 | None | 0.875 | 8 | 3 | 2012 | 2019 | ||||||||
|
NRAS proto-oncogene, GTPase | 0.390 | 0.808 | 0.49 |
|
disease | 0.460 | None | 1.000 | 15 | 4 | 1984 | 2019 | ||||||||
|
AKT serine/threonine kinase 2 | 0.474 | 0.769 | 0.64 |
|
disease | 0.460 | None | 1.000 | 8 | 1 | 2010 | 2018 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.400 | None | 0.972 | 424 | 13 | 1990 | 2020 | ||||||||
|
ROS proto-oncogene 1, receptor tyrosine kinase | 0.439 | 0.885 | 1.6E-72 |
|
disease | 0.400 | None | 0.989 | 179 | 2 | 2009 | 2020 | ||||||||
|
EMAP like 4 | 0.569 | 0.577 | 4.8E-04 |
|
disease | 0.400 | None | 0.994 | 177 | 1 | 2007 | 2020 | ||||||||
|
ERCC excision repair 1, endonuclease non-catalytic subunit | 0.445 | 0.846 | 1.6E-07 |
|
disease | 0.400 | None | 0.963 | 164 | 5 | 2002 | 2020 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.400 | None | 0.967 | 152 | 3 | 1997 | 2020 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.400 | None | 0.986 | 143 | 3 | 2002 | 2020 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 110 | 7 | 2003 | 2020 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.400 | None | 0.952 | 63 | 4 | 1989 | 2020 |