| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
group | 0.900 | strong | 0.955 | 22 | 0 | 1998 | 2020 | ||||||||
|
perforin 1 | 0.540 | 0.692 | 5.5E-06 |
|
group | 0.620 | strong | 1.000 | 2 | 0 | 2008 | 2015 | ||||||||
|
BLM RecQ like helicase | 0.535 | 0.808 | 1.5E-15 |
|
group | 0.610 | strong | 1.000 | 2 | 0 | 2002 | 2017 | ||||||||
|
WASP actin nucleation promoting factor | 0.529 | 0.808 | 1.00 |
|
group | 0.610 | strong | 1.000 | 2 | 0 | 2017 | 2019 | ||||||||
|
BCL2 apoptosis regulator | 0.291 | 0.885 | 0.56 |
|
group | 0.500 | None | 0.981 | 262 | 0 | 1987 | 2020 | ||||||||
|
enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.376 | 0.885 | 1.00 |
|
group | 0.500 | None | 1.000 | 44 | 3 | 2003 | 2020 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
group | 0.500 | None | 0.951 | 41 | 0 | 1995 | 2019 | ||||||||
|
MYD88 innate immune signal transduction adaptor | 0.414 | 0.923 | 0.12 |
|
group | 0.500 | None | 1.000 | 26 | 1 | 2011 | 2019 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
group | 0.500 | None | 0.923 | 13 | 1 | 1998 | 2018 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
group | 0.490 | None | 1.000 | 10 | 0 | 1997 | 2019 | ||||||||
|
SH2 domain containing 1A | 0.525 | 0.731 | 0.39 |
|
group | 0.470 | strong | 0.857 | 7 | 0 | 1998 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
group | 0.440 | None | 1.000 | 5 | 1 | 1997 | 2013 | ||||||||
|
DNA ligase 4 | 0.478 | 0.846 | 4.2E-06 |
|
group | 0.420 | strong | 1.000 | 3 | 0 | 2002 | 2017 | ||||||||
|
NRAS proto-oncogene, GTPase | 0.390 | 0.808 | 0.49 |
|
group | 0.410 | None | 1.000 | 2 | 1 | 1993 | 1997 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
group | 0.400 | None | 0.955 | 156 | 9 | 1986 | 2019 | ||||||||
|
CD274 molecule | 0.324 | 0.923 | 1.9E-02 |
|
group | 0.400 | None | 0.966 | 29 | 0 | 2011 | 2019 | ||||||||
|
Fas cell surface death receptor | 0.372 | 0.923 | 0.81 |
|
group | 0.400 | strong | 1.000 | 16 | 0 | 1995 | 2016 | ||||||||
|
notch receptor 1 | 0.369 | 0.885 | 1.00 |
|
group | 0.400 | None | 1.000 | 15 | 0 | 1998 | 2019 | ||||||||
|
cyclin dependent kinase inhibitor 2B | 0.417 | 0.769 | 7.3E-03 |
|
group | 0.400 | None | 1.000 | 12 | 0 | 1995 | 2011 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
group | 0.390 | None | 1.000 | 10 | 2 | 2004 | 2016 | ||||||||
|
cyclin dependent kinase 4 | 0.412 | 0.808 | 6.3E-02 |
|
group | 0.390 | None | 1.000 | 9 | 1 | 1996 | 2018 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
group | 0.370 | limited | 0.857 | 7 | 2 | 2012 | 2018 | ||||||||
|
TNF alpha induced protein 3 | 0.481 | 0.808 | 1.00 |
|
group | 0.360 | None | 1.000 | 6 | 1 | 2009 | 2016 | ||||||||
|
IKAROS family zinc finger 1 | 0.533 | 0.769 | 1.00 |
|
group | 0.340 | None | 1.000 | 5 | 0 | 1999 | 2008 | ||||||||
|
Janus kinase 3 | 0.505 | 0.731 | 5.9E-06 |
|
group | 0.340 | None | 1.000 | 4 | 0 | 2010 | 2018 |