Source: CLINVAR

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
erb-b2 receptor tyrosine kinase 3 0.473 0.690 6.7E-15
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.420 1.000 1 3 2016 2016
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.420 0.690 0.53
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.400 1 7 2016 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.417 0.759 1.00
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.400 1 8 2016 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.352 0.862 1.8E-03
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.200 0.941 2 9 1989 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.200 1.000 1 65 1992 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.321 0.828 0.38
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.150 1.000 1 5 1997 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.334 0.828 0.82
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.140 1.000 1 2 2005 2016
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
fibroblast growth factor receptor 2 0.398 0.759 1.00
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.130 1.000 1 3 2015 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.341 0.897 1.00
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.130 1.000 1 27 2005 2016
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.355 0.862 0.98
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.120 1.000 1 1 1987 2017
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
F-box and WD repeat domain containing 7 0.511 0.759 1.00
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.120 1.000 1 6 2006 2018
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
GNAS complex locus 0.443 0.793 0.71
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.110 1.000 1 2 2015 2016
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.399 0.793 1.00
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.110 1.000 1 2 2016 2016
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
fibroblast growth factor receptor 1 0.388 0.759 1.00
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.110 1.000 1 3 2015 2016
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
protein tyrosine phosphatase, non-receptor type 11 0.429 0.828 1.00
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.100 1 1 2016 2016
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
Raf-1 proto-oncogene, serine/threonine kinase 0.462 0.793 0.89
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.100 1 1 2016 2016
Entrez Id: 5605
Gene Symbol: MAP2K2
MAP2K2
mitogen-activated protein kinase kinase 2 0.559 0.586 0.97
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.100 1 2 2016 2016
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
mitogen-activated protein kinase kinase 1 0.459 0.759 0.91
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.100 1 4 2016 2016
Entrez Id: 9125
Gene Symbol: CNOT9
CNOT9
CCR4-NOT transcription complex subunit 9 0.785 0.172
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.100 1 2 2016 2016
Entrez Id: 9968
Gene Symbol: MED12
MED12
mediator complex subunit 12 0.528 0.655 1.00
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.100 1 1 2016 2016
Entrez Id: 5518
Gene Symbol: PPP2R1A
PPP2R1A
protein phosphatase 2 scaffold subunit Aalpha 0.590 0.517 0.99
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.100 1 2 2016 2016
Entrez Id: 5426
Gene Symbol: POLE
POLE
DNA polymerase epsilon, catalytic subunit 0.616 0.345 1.8E-25
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.100 1 1 2016 2016
Entrez Id: 387
Gene Symbol: RHOA
RHOA
ras homolog family member A 0.565 0.586 0.86
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.100 1 4 2016 2016
Entrez Id: 567
Gene Symbol: B2M
B2M
beta-2-microglobulin 0.499 0.759 0.48
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.100 1 3 2016 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.352 0.793 1.00
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
disease 0.100 1 3 2016 2016