| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.700 | None | 0.980 | 254 | 4 | 1985 | 2020 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.700 | None | 1.000 | 37 | 5 | 2002 | 2019 | ||||||||
|
ERCC excision repair 1, endonuclease non-catalytic subunit | 0.445 | 0.846 | 1.6E-07 |
|
disease | 0.600 | None | 0.949 | 38 | 11 | 2005 | 2019 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.500 | None | 0.985 | 1299 | 31 | 1988 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.500 | None | 0.942 | 555 | 33 | 1989 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.500 | None | 0.972 | 105 | 2 | 2002 | 2019 | ||||||||
|
tumor protein p63 | 0.362 | 0.769 | 1.00 |
|
disease | 0.500 | None | 0.958 | 21 | 4 | 1999 | 2019 | ||||||||
|
parkin RBR E3 ubiquitin protein ligase | 0.431 | 0.846 | 6.9E-07 |
|
disease | 0.500 | moderate | 1.000 | 12 | 6 | 2011 | 2020 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.500 | None | 0.846 | 11 | 2 | 2000 | 2018 | ||||||||
|
ERCC excision repair 6, chromatin remodeling factor | 0.507 | 0.808 | 5.2E-22 |
|
disease | 0.430 | limited | 1.000 | 3 | 4 | 2000 | 2009 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.400 | None | 0.972 | 107 | 5 | 1989 | 2020 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.400 | None | 0.979 | 47 | 1 | 1985 | 2019 | ||||||||
|
EPH receptor A3 | 0.497 | 0.692 | 1.2E-05 |
|
disease | 0.350 | None | 1.000 | 5 | 0 | 1999 | 2018 | ||||||||
|
neurotrophic receptor tyrosine kinase 2 | 0.479 | 0.808 | 1.00 |
|
disease | 0.350 | None | 1.000 | 5 | 0 | 2013 | 2019 | ||||||||
|
RPTOR independent companion of MTOR complex 2 | 0.592 | 0.615 | 1.00 |
|
disease | 0.330 | None | 1.000 | 3 | 0 | 2015 | 2017 | ||||||||
|
casein kinase 2 alpha 3 | 0.821 | 0.077 | 2.1E-10 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
interferon regulatory factor 1 | 0.468 | 0.769 | 0.99 |
|
disease | 0.310 | limited | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
neurotrophic receptor tyrosine kinase 3 | 0.522 | 0.692 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
RAD21 cohesin complex component | 0.528 | 0.846 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.300 | None | 0.984 | 60 | 0 | 1999 | 2019 | ||||||||
|
DNA methyltransferase 1 | 0.406 | 0.885 | 1.00 |
|
disease | 0.300 | None | 1.000 | 16 | 0 | 2004 | 2018 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.300 | None | 1.000 | 15 | 4 | 2004 | 2020 | ||||||||
|
DNA methyltransferase 3 alpha | 0.445 | 0.846 | 7.4E-39 |
|
disease | 0.280 | None | 1.000 | 8 | 0 | 2007 | 2019 | ||||||||
|
cholinergic receptor nicotinic alpha 5 subunit | 0.593 | 0.577 | 2.1E-06 |
|
disease | 0.200 | None | 0.933 | 59 | 9 | 2008 | 2018 | ||||||||
|
ERCC excision repair 2, TFIIH core complex helicase subunit | 0.420 | 0.846 | 7.1E-20 |
|
disease | 0.200 | None | 0.965 | 56 | 9 | 2001 | 2019 |