Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0004096
Disease: Asthma
Asthma
0.700 Biomarker RGD (2) IL-13 protein in supernatants of asthmatic lymphocytes was higher than that produced by normal control lymphocytes, and was significantly increased by EGF treatment. 20819635

2010

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0004096
Disease: Asthma
Asthma
0.700 Biomarker RGD Significant increases in the number of cells, especially eosinophils, and IL13 but not IFN-gamma concentration in BALF were observed in the RO+BA group compared with the BA group. 18222984

2008

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0004096
Disease: Asthma
Asthma
0.700 Biomarker RGD Pharmacological assessment of the nitric-oxide synthase isoform involved in eosinophilic inflammation in a rat model of sephadex-induced airway inflammation. 12604708

2003

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.560 Therapeutic RGD Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin-induced lung injury. 19154443

2009

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0035455
Disease: Rhinitis
Rhinitis
0.260 Biomarker RGD Spatial and temporal expression of CCR3 and the common beta chain of the IL-3, IL-5 and GM-CSF receptor in the nasal epithelium and lymphoid tissues in a rat model of allergic rhinitis. 20696593

2010

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0016059
Disease: Fibrosis
Fibrosis
0.240 Therapeutic RGD P-selectin inhibition decreases post-thrombotic vein wall fibrosis in a rat model. 12947342

2003

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0243026
Disease: Sepsis
Sepsis
0.230 Biomarker RGD Protective effect of Ulinastatin against murine models of sepsis: inhibition of TNF-α and IL-6 and augmentation of IL-10 and IL-13. 21159497

2012

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0036330
Disease: Schistosomiasis mansoni
Schistosomiasis mansoni
0.230 Therapeutic RGD Interleukin-13 and IgE production in rat experimental schistosomiasis. 10903803

2000

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0027721
Disease: Lipoid nephrosis
Lipoid nephrosis
0.210 Biomarker RGD Overexpression of interleukin-13 induces minimal-change-like nephropathy in rats. 17429054

2007

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0740392
Disease: Infarction, Middle Cerebral Artery
Infarction, Middle Cerebral Artery
0.200 Biomarker RGD Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke. 23028794

2012

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C1739363
Disease: Prostatic Hypertrophy
Prostatic Hypertrophy
0.200 Biomarker RGD LHRH antagonist Cetrorelix reduces prostate size and gene expression of proinflammatory cytokines and growth factors in a rat model of benign prostatic hyperplasia. 20945403

2011

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0030305
Disease: Pancreatitis
Pancreatitis
0.200 Biomarker RGD This finding provides an unequivocal evidence of IL-13 participation in pancreatic fibrosis, illustrating a new strategy for chronic pancreatitis. 20100461

2010

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
0.200 Biomarker RGD Lastly, patients with interstitial lung disease had elevated IL-6 and patients with pulmonary hypertension had elevated IL-6 and IL-13. 19799786

2009

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0014869
Disease: Peptic Esophagitis
Peptic Esophagitis
0.200 Biomarker RGD Significant increases in the number of cells, especially eosinophils, and IL13 but not IFN-gamma concentration in BALF were observed in the RO+BA group compared with the BA group. 18222984

2008

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury
0.200 Biomarker RGD Systemic gene therapy with interleukin-13 attenuates renal ischemia-reperfusion injury. 18354382

2008

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0018129
Disease: Graft Rejection
Graft Rejection
0.200 Biomarker RGD Increased expression of non-interleukin-2 T cell growth factors and their implications during liver allograft rejection in rats. 17532783

2007

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0018129
Disease: Graft Rejection
Graft Rejection
0.200 Therapeutic RGD IL-13 prolongs allograft survival: association with inhibition of macrophage cytokine activation. 17331844

2007

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0001306
Disease: Acute alcoholic liver disease
Acute alcoholic liver disease
0.200 Biomarker RGD Effect of tea polyphenol on cytokine gene expression in rats with alcoholic liver disease. 16698589

2006

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0024116
Disease: Lung Diseases, Fungal
Lung Diseases, Fungal
0.200 Biomarker RGD Enhanced allergic inflammation and airway responsiveness in rats with chronic Cryptococcus neoformans infection: potential role for fungal pulmonary infection in the pathogenesis of asthma. 16544260

2006

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
0.200 Biomarker RGD To study the role of pro-inflammatory cytokines including tumor necrosis factor-alpha(TNF-alpha), interleukin-1beta(IL-1beta), IL-6, and anti-inflammatory cytokines including IL-4, IL-10, and IL-13 in acute lung injury(ALI). 15461830

2004

Entrez Id: 3596
Gene Symbol: IL13
IL13
CUI: C0002390
Disease: Extrinsic allergic alveolitis
Extrinsic allergic alveolitis
0.200 Biomarker RGD Regulation of acute lung inflammatory injury by endogenous IL-13. 9916735

1999