Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0004096
Disease: Asthma
Asthma
0.600 Biomarker RGD Role of the extracellular signal-regulated kinase 1/2 signaling pathway in regulating the secretion of bronchial smooth muscle cells in a rat model of chronic asthma. 18208670

2008

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0020500
Disease: Hyperoxaluria
Hyperoxaluria
0.500 Biomarker RGD NF-kappaB and chemokine-cytokine expression in renal tubulointerstitium in experimental hyperoxaluria. Role of the renin-angiotensin system. 16284884

2005

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.290 Biomarker RGD Dietary fatty acid unsaturation levels, lipoprotein oxidation and circulating chemokine in experimentally induced atherosclerotic rats. 16259780

2005

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0014175
Disease: Endometriosis
Endometriosis
0.280 Biomarker RGD Cytokine and chemokine expression in a rat endometriosis is similar to that in human endometriosis. 18595729

2008

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.240 Biomarker RGD CCR3- and CXCR4-mediated interactions regulate migration of CD34+ human bone marrow progenitors to ischemic myocardium and subsequent tissue repair. 18954648

2008

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0028754
Disease: Obesity
Obesity
0.240 Biomarker RGD RANTES and MCP-1 serum levels were increased in obese vs lean Zucker rats and significantly reduced by long-term treatment with rimonabant, which slowed weight gain in rats with the metabolic syndrome. 18469848

2008

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.220 Biomarker RGD Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats. 19535570

2009

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.220 Biomarker RGD Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats. 19535570

2009

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
0.220 Biomarker RGD Pretreatment with antibodies against RANTES/CCL5 prevented the hyperalgesic response, indicating that RANTES/CCL5 is able to interfere with the control of hyperalgesia at the level of the periaqueductal grey and suggesting that chemokine blockers could have analgesic properties. 18656466

2008

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
0.220 Biomarker RGD Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: a mechanism for the development of chronic sensitization of peripheral nociceptors. 18076762

2007

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0021368
Disease: Inflammation
Inflammation
0.220 Biomarker RGD In our study, we established the involvement of RANTES in an in vivo model of chronic inflammation induced by potassium permanganate, leading to calcified granulomas. 17164972

2007

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.220 Biomarker RGD DNA vaccination with naked DNA encoding MCP-1 and RANTES protects against renal injury in adriamycin nephropathy. 15882261

2005

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0030193
Disease: Pain
Pain
0.220 Biomarker RGD Chemokines and glycoprotein120 produce pain hypersensitivity by directly exciting primary nociceptive neurons. 11438578

2001

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest
0.210 Biomarker RGD Minocycline reduces neuronal death and attenuates microglial response after pediatric asphyxial cardiac arrest. 19756023

2010

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.210 Biomarker RGD Impact of chronic anticholesterol therapy on development of microvascular rarefaction in the metabolic syndrome. 19905967

2009

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0042164
Disease: Uveitis
Uveitis
0.210 Biomarker RGD Th1- and Th2-related chemokine and chemokine receptor expression on the ocular surface in endotoxin-induced uveitis. 19104678

2008

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0030305
Disease: Pancreatitis
Pancreatitis
0.210 Biomarker RGD Bile-pancreatic juice exclusion promotes Akt/NF-kappaB activation and chemokine production in ligation-induced acute pancreatitis. 16843865

2006

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0001306
Disease: Acute alcoholic liver disease
Acute alcoholic liver disease
0.200 Therapeutic RGD Optimal ratio of 18α- and 18β-glycyrrhizic acid for preventing alcoholic hepatitis in rats. 31258651

2019

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 ModifyingMutation RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 ModifyingMutation RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 2
0.200 ModifyingMutation RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 2
0.200 Therapeutic RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0270824
Disease: Visual seizure
Visual seizure
0.200 Biomarker RGD Role of CCR5 and its ligands in the control of vascular inflammation and leukocyte recruitment required for acute excitotoxic seizure induction and neural damage. 20940264

2011