×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
The cardiovascular phenotype of a mouse model of acromegaly.
19269870
2009
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
Growth hormone receptor deficiency results in blunted ghrelin feeding response, obesity, and hypolipidemia in mice.
16174655
2006
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
Comparing adiposity profiles in three mouse models with altered GH signaling.
15231300
2004
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
Puberty is delayed in male growth hormone receptor gene-disrupted mice.
12185100
2003
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
Impact of growth hormone resistance on female reproductive function: new insights from growth hormone receptor knockout mice.
12297526
2002
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth.
11133160
2001
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice.
11336996
2001
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice.
10974652
2000
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
We chose to study the effects of loss of GH signaling on growth and aging in a mouse model for Laron Syndrome (LS ) in which the GHR /BP gene has been disrupted.
10875265
2000
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
Protection against diabetes-induced nephropathy in growth hormone receptor/binding protein gene-disrupted mice.
10614635
2000
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
Disproportional skeletal growth and markedly decreased bone mineral content in growth hormone receptor -/- mice.
10631109
2000
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
Deficits in female reproductive function in GH-R-KO mice; role of IGF-I.
10342852
1999
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
Pituitary and testicular function in growth hormone receptor gene knockout mice.
10067829
1999
×
Entrez Id:
2690
Gene Symbol:
GHR
GHR
Laron Syndrome
1.000
Biomarker
MGD
These findings indicate that the GHR /BP-deficient mouse (Laron mouse) is a suitable model for human Laron syndrome that will prove useful for the elucidation of many aspects of GHR /BP function that cannot be obtained in humans.
9371826
1997