Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Concerted action of perforin and granzymes is critical for the elimination of Trypanosoma cruzi from mouse tissues, but prevention of early host death is in addition dependent on the FasL/Fas pathway. 12594834

2003
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Anti-DNA B cells in MRL/lpr mice show altered differentiation and editing pattern. 12486097

2002
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Enhanced and accelerated lymphoproliferation in Fas-null mice. 8700897

1996
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Reduced cell-cell communication in a spontaneous murine model of autoimmune thyroid disease. 7628400

1995
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver. 7581453

1995
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Transfer of Sjögren's syndrome-like autoimmune lesions into SCID mice and prevention of lesions by anti-CD4 and anti-T cell receptor antibody treatment. 7957574

1994
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Comparative influence of steroid hormones and immunosuppressive agents on autoimmune expression in lacrimal glands of a female mouse model of Sjögren's syndrome. 8163351

1994
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Serological and histological characterization of the new mutant strain of lpr mice, CBA/KlJms-lprcg/lprcg. 2302830

1990
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD A new allele of the lpr locus, lprcg, that complements the gld gene in induction of lymphadenopathy in the mouse. 2406366

1990
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice. 3009614

1986
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Dissociation of severe lupus-like disease from polyclonal B cell activation and IL 2 deficiency in C3H-lpr/lpr mice. 6610701

1984
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene. 6975351

1981
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice. 6444324

1980
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes. 762500

1979
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		1.000 Biomarker MGD Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains. 309911

1978