Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0021368
Disease: Inflammation
Inflammation
0.570 GeneticVariation LHGDN In conclusion, although COX-2 -765G>C and IL-6 -174G>C polymorphisms were associated with inflammation, consuming a MD (either supplemented with virgin olive oil or nuts) reduced the concentration of inflammation markers regardless of these polymorphisms. 19056642

2009

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0021368
Disease: Inflammation
Inflammation
0.570 Biomarker LHGDN Cyclooxygenase-2 expression on urothelial and inflammatory cells of cystoscopic biopsies and urine cytology as a possible predictive marker for bladder carcinoma. 19161536

2009

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0021368
Disease: Inflammation
Inflammation
0.570 Biomarker LHGDN Overall, our results suggest that certain alkamides derived from E. angustifolia roots may contribute to the pharmacological action of the herbal extract by inhibiting COX-2-dependent PGE2 formation at sites of inflammation. 17599805

2007

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0021368
Disease: Inflammation
Inflammation
0.570 Biomarker LHGDN To investigate the YKL-40 presence in human lumbar disc tissue culture and its possible relationships with some substances relevant in inflammation such as cyclooxygenase-2 (COX-2) and nitric oxide (NO). 17631744

2007

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0021368
Disease: Inflammation
Inflammation
0.570 Biomarker LHGDN Chronic inflammation, associated with expression of cyclooxygenase-2 (COX-2) and prostaglandins, predisposes to malignancy. 15863442

2005

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0021368
Disease: Inflammation
Inflammation
0.570 Biomarker LHGDN Taken together, our results indicate that cell-cell contacts induce an actively programmed necrotic process that functionally involves COX-2, a known hallmark of inflammation and cancer. 14555963

2004

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0021368
Disease: Inflammation
Inflammation
0.570 Biomarker LHGDN The activation of COX-2 may be one of the distinct host degradative pathways in the pathogenesis of microbial-induced pulpal/periapical inflammation. 12701770

2003