Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0021368
Disease: Inflammation
Inflammation
0.350 Biomarker LHGDN These results suggest that TLR2 and TLR4 may play a role in aortic valve inflammation and stenosis. 17942642

2008

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0021368
Disease: Inflammation
Inflammation
0.350 Biomarker LHGDN These observations support the notion of a potential role for activation through TLR-2 and TLR-4 in the inflammation and joint destruction of RA. 17599732

2007

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0021368
Disease: Inflammation
Inflammation
0.350 AlteredExpression LHGDN These findings suggest that NADPH oxidase activation, mRNA stabilization, and MAPK signaling pathways play critical roles in LPS-enhanced TLR4 expression in HASMCs, which contributes to vascular inflammation and cardiovascular disorders. 17008589

2006

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0021368
Disease: Inflammation
Inflammation
0.350 AlteredExpression LHGDN Up-regulation of Toll-like receptors 2, 3 and 4 in allergic rhinitis. 16146574

2005

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0021368
Disease: Inflammation
Inflammation
0.350 Biomarker LHGDN TLR4 mediates human retinal pigment epithelial endotoxin binding and cytokine expression. 17057796

2005