Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.800 GeneticVariation LHGDN study examined the presence of mutations in TP53 at codon 249 (Ser-249, considered as a hallmark of mutagenesis by aflatoxin) and in CTNNB1 in circulating free DNA of patients with hepatocellular carcinoma or chronic liver disease from Alexandria, Egypt 18313840

2008

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.800 AlteredExpression LHGDN Correlation between beta-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma. 18282277

2008

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.800 AlteredExpression LHGDN In hepatocellular carcinoma (HCC), there is a negative correlation between the positive expression of p130Cas and the normal expression of E-cadherin/beta-catenin/plays important roles in the invasion, metastasis and prognosis of HCC. 18842495

2008

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.800 AlteredExpression LHGDN hepatocellular carcinomas (HCC) with extensive methylation harbor frequent beta-catenin mutations; HCCs with high levels of chromosomal instability are associated with p53 mutations, suggesting presence of two independent pathways for pathogenesis of HCC 17510384

2007

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.800 AlteredExpression LHGDN The beta-catenin expression in hepatocellular carcinoma cells was heterogeneous among types of hepatitis viral infection 15832407

2005

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.800 AlteredExpression LHGDN These results indicate that the altered expression of beta-catenin, but not cyclin D1, in hepatocellular carcinoma may play an important role in tumor progression by stimulating tumor cell proliferation. 12692418

2003

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.800 AlteredExpression LHGDN Overexpression of beta-catenin is associated with hepatocellular carcinoma 12969793

2003

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.800 AlteredExpression LHGDN Abnormal beta-catenin gene expression with invasiveness of primary hepatocellular carcinoma in China. 11819825

2002

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.800 AlteredExpression LHGDN Expression and prognostic roles of beta-catenin in hepatocellular carcinoma: correlation with tumor progression and postoperative survival 11839663

2002