Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2719
Gene Symbol: GPC3
GPC3
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.600 AlteredExpression LHGDN Collectively, these results suggest that progression of hepatocellular carcinoma is associated with upregulation of GPC3. 16682817

2006

Entrez Id: 2719
Gene Symbol: GPC3
GPC3
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.600 AlteredExpression LHGDN GPC3 immunostaining was positive in all HCCs and negative in dysplastic nodules (22/22 vs 0/14, respectively, P < .001). 17087938

2006

Entrez Id: 2719
Gene Symbol: GPC3
GPC3
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.600 Biomarker LHGDN Our study raises the possibility that these GPC3 peptides may therefore be applicable to cancer immunotherapy for a large number of HCC patients. 16675560

2006

Entrez Id: 2719
Gene Symbol: GPC3
GPC3
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.600 Biomarker LHGDN We report here that a mutant GPC3 that cannot be processed by convertases is still able to play its stimulatory role in Wnt activity and HCC growth. 16227623

2005

Entrez Id: 2719
Gene Symbol: GPC3
GPC3
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.600 AlteredExpression LHGDN By Western blot analysis carried out with a monoclonal anti-GPC3 antibody we generated, the GPC3 protein was found to be overexpressed in 6 hepatoma cell lines, HepG2, Hep3B, HT17, HuH6, HuH7 and PLC/PRF/5, as well as 22 tumors (42.3%). 12478660

2003

Entrez Id: 2719
Gene Symbol: GPC3
GPC3
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.600 AlteredExpression LHGDN We conclude that GPC3 is a good molecular marker for HCC. 12824919

2003