Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET FMR1 gene polymorphisms, dopaminergic (DAT, DRD, COMT), serotonin (5-HTTLPR, HTR1A, HTR2A), interleukins, MCR1, HCN (potassium channel), neurorregulinas, GABAergic (GABA, GAD, DBI) DBI, GABA (Gabra) receptors and GAD genes (GAD1, GAD2) appear to contribute to generate condition of depression or anxiety like. 25106036

2014

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET The frontal abnormality of patients with depression had certain 5-HT genetic basis, and 5-HT2A receptor CC allele and MAOA-H genotype had synergistic effect on the activity abnormality when recognizing negative emotion in right frontal middle gyrus of patients with depression. 24314147

2014

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Associations between suicidal ideation and 5-HTTLPR, STin2 VNTR, 5-HTR2a 1438A/G, and 5-HTR2a 102T/C genotypes were estimated using logistic regression models, and gene-gene interactions were investigated using the generalized multifactor dimensionality reduction method after adjustment for potential covariates, including depression. 23973249

2014

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET The HTR2A-rs7997012 is worthy of further investigation in studies examining factors that are related to depression course and outcome. 23537781

2013

Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Targeted analysis of HTR2A in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study reveals associations between functional variants and depression severity or citalopram response. 23158458

2013