Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.700 Biomarker PSYGENET Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice. 25583186

2015

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.700 Biomarker PSYGENET The risk for major depression conferred by childhood maltreatment is multiplied by BDNF and SERT genetic vulnerability: a replication study. 25510949

2015

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.700 Biomarker PSYGENET Genetic moderation of child maltreatment effects on depression and internalizing symptoms by serotonin transporter linked polymorphic region (5-HTTLPR), brain-derived neurotrophic factor (BDNF), norepinephrine transporter (NET), and corticotropin releasing hormone receptor 1 (CRHR1) genes in African American children. 25422957

2014

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.700 Biomarker PSYGENET Epigenetic and epistatic interactions between serotonin transporter and brain-derived neurotrophic factor genetic polymorphism: insights in depression. 24972302

2014

Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.700 Biomarker PSYGENET Our findings reveal that 5-HTTLPR polymorphism modulates distressed feelings and brain activities associated with negative self-schema and suggest a potential neurogenetic susceptibility mechanism for depression. 23588187

2014