Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0004096
Disease: Asthma
Asthma
0.300 Biomarker RGD Tissue plasminogen activator activity was significantly decreased in asthmatic animals (4.48 +/- 0.4 vs. 6.7 +/- 0.3 ng/ml for OVA/OVA and OVA/VEH; p < 0.05), and PAI-1 activity was statistically significantly higher in asthma rats (0.8 +/- 0.05 vs. 0.5 +/- 0.03 ng/ml for OVA/OVA vs. OVA/VEH; p < 0.05). alpha2-Antiplasmin was higher in rats receiving OVA sensitization than in those that were sham sensitized (p < 0.05). 18594148

2008

Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0004096
Disease: Asthma
Asthma
0.300 Biomarker RGD Immunohistochemical staining for PAI-1in the lungs of asthmatic animals showed very strong PAI-1 expression in lung inflammatory cells. 18594148

2008

Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0004096
Disease: Asthma
Asthma
0.300 Biomarker RGD We have demonstrated for the first time the existence of PAI-1 in lung inflammatory cells of rats with asthma. 18594148

2008