Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0004096
Disease: Asthma
Asthma
0.400 Therapeutic RGD In situ hybridization showed that the mRNA expression of STAT6 around the bronchus of asthma group (0.180 +/- 0.013) was significantly higher than that of the control group (0.091 +/- 0.012) (P < 0.01), while that of DXM group (0.114 +/- 0.010) was significantly lower than that of asthma group. 16083555

2010

Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0004096
Disease: Asthma
Asthma
0.400 Therapeutic RGD (3) Immunohistochemistry showed that the protein content of STAT6 around the bronchus of asthma group (0.171 +/- 0.025) was significantly higher than that of the control group (0.082 +/- 0.022) (P < 0.01), while that of DXM group (0.114 +/- 0.013) was significantly lower than that of asthma group.The epithelial cells were the cells. 16083555

2010

Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0004096
Disease: Asthma
Asthma
0.400 Therapeutic RGD [Expression of signal transducer and activator of transcription 6 in rat asthma model and the modulatory effect of dexamethasone]. 16083555

2010

Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0004096
Disease: Asthma
Asthma
0.400 Therapeutic RGD To study the expression of signal transducer and activator of transcription 6 and its mRNA in rat asthma model and the modulatory effect of dexamethasone (DXM). 16083555

2010

Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0004096
Disease: Asthma
Asthma
0.400 Therapeutic RGD STAT6 protein and STAT6 mRNA were found strongly expressed in rat asthma model and the epithelial cells were the chief expressing cells. 16083555

2010

Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0004096
Disease: Asthma
Asthma
0.400 Biomarker RGD The respiratory rate, expiratory flow, percentage of eosinophils in BALF inflammatory cells, peripheral blood IgE concentration, mRNA expression of STAT6 and NF-kappaB of the asthma group were (206 +/- 11) times/min, (77 +/- 8) microl/s, 24.8% +/- 1.3%, (72.5 +/- 8.1) ng/ml, 0.294 +/- 0.048, and 0.686 +/- 0.052 respectively, all significantly higher than those of the low dose treatment group [(183 +/- 9) times/min, (64 +/- 5) microl/s, 18.5% +/- 3.1%, (63.4 +/- 4.8) ng/ml, 0.229 +/- 0.038, and 0.613 +/- 0.062 respectively, all P < 0.05] and those of the high dose treatment group [(181 +/- 11) times/min, (57 +/- 4) microl/s, 14.7% +/- 2.1%, (41.4 +/- 7.4) ng/ml, 0.194 +/- 0.076, and 0.352 +/- 0.267, all P < 0.05]. 19087723

2009