×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
(3) Also, the neu gene encoded protein p185 has been associated with a more aggressive clinical course in adenocarcinomas .
1962774
1990
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
AlteredExpression
BEFREE
HER-2/neu gene amplification by FISH predicts poor survival in Barrett's esophagus-associated adenocarcinoma .
10665910
2000
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
AlteredExpression
BEFREE
HER-2/neu overexpression was detected in 27% of the tumors of different histological types including adenocarcinomas , large cell carcinomas, and squamous cell carcinomas.
10928158
2000
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
AlteredExpression
BEFREE
HER-2/neu is overexpressed on a variety of human adenocarcinomas and overexpression has been associated with a poor prognosis.
10965998
2000
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
HER2 positivity by at least one of the three techniques was most common in adenocarcinomas , at 29% (42 of 143).
14614004
2003
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
HER-2/neu overexpression was significantly associated with histologic subtype: 19 adenocarcinomas (19/82, 23%) versus 4 squamous cell carcinomas (4/44, 9%) overexpressed Her-2/neu (P = 0.04).
14639106
2003
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
AlteredExpression
BEFREE
HER2 -neu overexpression was found in 19 tumors (17.1%) and was significantly more common in adenocarcinomas than in squamous cell carcinomas (P = 0.035).
14734462
2004
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
AlteredExpression
BEFREE
HER-2/neu is overexpressed in approximately one-third of esophageal adenocarcinomas .
15581047
2004
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
GeneticVariation
BEFREE
HER2 mutations were significantly more frequent in never smokers (3.2%, 8 of 248; P=0.02) and adenocarcinoma histology (2.8%, 11 of 394; P=0.003).
15753357
2005
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
AlteredExpression
BEFREE
HER-2/neu and TOPOIIalpha amplification/overexpression might discriminate between BO and dysplasia/ADC .
20557373
2010
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
AlteredExpression
BEFREE
Her-2 protein expression was investigated in 341 esophageal carcinomas [152 squamous cell carcinomas (SCC), 189 adenocarcinomas (AC )], 39 cases of Barrett mucosa, and 11 cases of squamous cell dysplasia.
21107094
2010
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
CTD_human
HER2 Testing in Gastric/Gastroesophageal Junction Adenocarcinomas : Unique Features of a Familiar Test.
21673877
2011
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
HER2 in situ hybridization in gastric and gastroesophageal adenocarcinoma : comparison of automated dual ISH to FISH.
23455182
2013
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
HER2 expression is consistently absent in gastric NECs, regardless of HER2 amplification status or association with HER2 -positive adenocarcinoma /dysplasia components.
24329753
2014
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
HER2 -dependent signalling pathway is deregulated in a subset of colon adenocarcinomas .
24659651
2014
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
GeneticVariation
BEFREE
HER2 mutations were detected in 46 (3.6%) of the NSCLCs, with mutations only present in the ADC .
25468202
2015
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
HER2 positivity occurs in 15.6 % of invasive gastroesophageal adenocarcinoma in Western patients, of which the majority is esophageal primary tumors and of the intestinal tumor type.
25544671
2015
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
Human epidermal growth factor receptor 2 testing in gastric and gastroesophageal junction adenocarcinomas : role of the gastroenterologist.
25805465
2015
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
HER2 -positive (HER2 (+)) breast adenocarcinomas are a heterogeneous group in which hormone receptor (HR) status influences therapeutic decisions and patient outcome.
26227964
2015
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
HER2 insertion could define a distinct subset of NSCLC, which had a higher prevalence among females, nonsmokers, and adenocarcinoma .
27008586
2017
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
GeneticVariation
BEFREE
HER2 mutations are observed in mucinous adenocarcinoma and adenocarcinoma with micropapillary features.
27403614
2016
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
HER2 status is an independent prognostic biomarker in gastroesophageal adenocarcinomas receiving epirubicin-based chemotherapy.
27530622
2017
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
GeneticVariation
BEFREE
HER2 mutations were more frequently encountered in females, non-smokers and adenocarcinoma .
27825109
2016
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma : Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology.
27841667
2016
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
Adenocarcinoma
0.400
Biomarker
BEFREE
HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma : Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology.
28077399
2016