Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE Here we show that CD24 can be the dominant innate immune checkpoint in ovarian cancer and breast cancer, and is a promising target for cancer immunotherapy. 31367043

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE CD24 marker (a differentiation marker for the breast cancer cells) was significantly reduced in the mammospheres generated from MCF7 and SKBR3, during three passages. 31423948

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 AlteredExpression BEFREE Reduced CD24 expression was observed in the MDA-MB-468 CTCs, consistent with the 'breast cancer stem cell' phenotype, and metastatic deposits in this model mostly resembled the primary xenografts, consistent with the mesenchymal-epithelial transition paradigm. 31190270

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE Downregulation of FOXD2‑AS1 decreased the percentage of CD44 antigen+/signal transducer CD24- in breast cancer stem cell (BCSC) cells, and decreased the expression of numerous stem factors, including Nanog, octamer‑binding transcription factor 4 (Oct4), and sex determining region Y‑box 2 (SOX2), and inhibited the epithelial‑mesenchymal transition process. 30628646

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE Cluster of differentiation (CD)44+/CD24- breast cancer cells have stem cell‑like characteristics and are potent initiators of tumorigenesis. 30664162

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE The results revealed that the expression of NY-ESO-1/CD44/CD24 was associated with breast cancer metastasis. 31579408

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 AlteredExpression BEFREE Breast cancer samples with advanced histological grade also showed higher CD44 (p = 0.03) and CD24 expression (p = 0.05). 31075227

2019

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE Cluster of differentiation (CD) 133<sup>+</sup>/CD44<sup>+</sup> prostate CSCs and CD 44<sup>+</sup>/CD24 breast CSCs were isolated from the DU-145 human prostate cancer and MCF-7 human breast cancer cell lines, respectively, using FACSAria flow cytometry cell sorting. 29300112

2018

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE Effect of curcumin on the cell surface markers CD44 and CD24 in breast cancer. 29693159

2018

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 AlteredExpression BEFREE Our results indicated that the expression of CD24 was a significant poor prognostic factor in ER-positive early breast cancer treated with adjuvant tamoxifen. 29416796

2018

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE Previously reported data showed that IMP3 expression was significantly upregulated in CD44+CD24-ESA+ cell cluster from breast cancer tissues. 29771420

2018

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE In addition, CD24 and SDC1 can serve as prognostic indicators for breast cancer. 30001552

2018

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 AlteredExpression BEFREE Expression of AR and CD24 in stage I-III invasive BCa correlates with favorable clinicopathological features and delineates a subgroup of patients with better disease-free survival. 29843115

2018

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 AlteredExpression BEFREE Growth inhibition of the breast cancer cell lin e MDA‑MB‑231 by ivermectin was investigated in the total cell population, in cell spheroids and in sorted cells that expressed cluster of differentiation (CD)44+/CD24‑. 29257278

2018

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 AlteredExpression BEFREE Publications addressing the associations of CD24 or CD44 expression with survival outcome in breast cancer were selected for the meta-analysis according to defined criteria. 27470135

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE The electrochemical signal enhancement achieved via gold nanoparticles and grapheme oxide system allowed for sensitive detection of the breast cancer biomarker ERBB2 and the control marker CD24. 28802177

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE This study contributes to determining the role of CD24 in breast cancer. 28179302

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 AlteredExpression BEFREE Quantitative PCR results showed that the expression levels of CD24 and B7-H3 mRNA in breast cancer tissues were significantly higher than those in adjacent tissues (P<0.05). 29344150

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE CD44/CD24 and ALDH1 are widely used cancer stem cell (CSC) markers in breast cancer. 29062075

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE Expression profiling revealed 780 genes for which the expression level was affected by the loss of DIP2C, including the tumour-suppressor encoding CDKN2A gene, the epithelial-mesenchymal transition (EMT) regulator-encoding ZEB1, and CD44 and CD24 that encode breast cancer stem cell markers. 28716088

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE Our results indicate that bone-derived osteopontin promotes the migration, tumorsphere-forming ability and colony-forming ability of whole population and ALDHhiCD44+CD24- breast cancer cells in bone marrow-conditioned media (an ex vivo representation of the bone microenvironment) (p≤0.05). 28498874

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE This meta-analysis suggested that CD24 is an efficient prognostic factor in breast cancer. 28315505

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE The present study aimed to explore the role of the combination of Twist1 expression in metastasized ALN and the serum level of CA15‑3 in evaluating the prognosis of patients with breast cancer. cluster of differentiation (CD)44, CD24, aldehyde dehydrogenase (ALDH)1 and Twist1 expression in normal and metastasized ALN from 102 patients with breast cancer were detected using laser confocal microscopy and the expression of the genes evaluated by reverse transcription‑quantitative polymerase chain reaction; E‑cadherin, N‑cadherin and vimentin expression was also tested by western blotting. 28112378

2017

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE Here, we describe a relationship between CD24 and Sonic Hedgehog (SHH), and reveal a role for this relationship in the induction of a malignant phenotype of breast cancer. 26797459

2016

Entrez Id: 100133941
Gene Symbol: CD24
CD24
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.100 Biomarker BEFREE Fluorescence Activated Cell Sorting (FACS) analysis showed the presence of a variable fraction of CD44(+)CD24(-) cells in 25 out of 25 breast cancer samples. 26546432

2016