×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Malignant neoplasm of stomach
0.800
Biomarker
CTD_human
Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.
24816253 2014
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Malignant neoplasm of stomach
0.800
Biomarker
CTD_human
Silencing of CDH1 by promoter CpG island methylation was shown in gastric cancer , precancerous lesion, and Helicobacter pylori-infected chronic gastritis.
19184424 2010
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Malignant neoplasm of stomach
0.800
Biomarker
CTD_human
We hypothesized that CDH1 genomic rearrangements would be found in HDGC and identified 160 families with either two gastric cancers in first-degree relatives and with at least one diffuse gastric cancer (DGC) diagnosed before age 50, or three or more DGC in close relatives diagnosed at any age.
19168852 2009
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Malignant neoplasm of stomach
0.800
Biomarker
CTD_human
We screened a series of 66 young gastric cancer probands for germline CDH1 mutations, and two novel missense alterations together with an intronic variant were identified.
12588804 2003
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Malignant neoplasm of stomach
0.800
Biomarker
CTD_human
However, only a minority of familial gastric cancers can be accounted for by CDH1 mutations.
10072428 1999
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Malignant neoplasm of stomach
0.800
Biomarker
CTD_human
E-cadherin germline mutations in familial gastric cancer.
9537325 1998
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Malignant neoplasm of stomach
0.800
GeneticVariation
UNIPROT
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Malignant neoplasm of stomach
0.800
CausalMutation
CGI
×
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
Malignant neoplasm of stomach
0.700
Biomarker
CTD_human
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes.
22484628 2012
×
Entrez Id: 4233
Gene Symbol: MET
MET
Malignant neoplasm of stomach
0.700
Biomarker
CTD_human
Crizotinib thus shows a marked antitumor action both in vitro and in vivo specifically in gastric cancer cells positive for MET amplification.
22729845 2012
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
Malignant neoplasm of stomach
0.700
Biomarker
CTD_human
Thus, combined expression of MYC, EGFR and FGFR2 is predictive of poor survival in CF-treated metastatic gastric cancer patients.
21173787 2012
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Malignant neoplasm of stomach
0.700
Biomarker
CTD_human
MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib.
22042947 2011
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
Malignant neoplasm of stomach
0.700
Biomarker
CTD_human
Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase.
21936542 2011
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Malignant neoplasm of stomach
0.700
Biomarker
CTD_human
We analyzed the association between HER2 overexpression and the clinicopathologic characteristics of advanced GC .
21532492 2011
×
Entrez Id: 4233
Gene Symbol: MET
MET
Malignant neoplasm of stomach
0.700
Biomarker
CTD_human
MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib.
22042947 2011
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Malignant neoplasm of stomach
0.700
Biomarker
CTD_human
High dose fluorouracil/leucovorin-based chemotherapy may have the potential to reverse the adverse effects resulting from erbB2 gene amplification in gastric cancer .
15640503 2004
×
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
Malignant neoplasm of stomach
0.700
CausalMutation
CGI
×
Entrez Id: 4233
Gene Symbol: MET
MET
Malignant neoplasm of stomach
0.700
GeneticVariation
UNIPROT
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Malignant neoplasm of stomach
0.700
GenomicAlterations
CGI
×
Entrez Id: 324
Gene Symbol: APC
APC
Malignant neoplasm of stomach
0.700
Biomarker
CTD_human
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Malignant neoplasm of stomach
0.700
CausalMutation
CGI
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
Malignant neoplasm of stomach
0.700
GenomicAlterations
CGI
×
Entrez Id: 324
Gene Symbol: APC
APC
Malignant neoplasm of stomach
0.700
CausalMutation
CGI
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
Malignant neoplasm of stomach
0.700
CausalMutation
CGI
×
Entrez Id: 4233
Gene Symbol: MET
MET
Malignant neoplasm of stomach
0.700
GenomicAlterations
CGI