Source: GWASDB

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 965
Gene Symbol: CD58
CD58
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis. 24234648

2014
Entrez Id: 3575
Gene Symbol: IL7R
IL7R
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088

2011
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. 22190364

2011
Entrez Id: 965
Gene Symbol: CD58
CD58
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. 22190364

2011
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088

2011
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088

2011
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088

2011
Entrez Id: 965
Gene Symbol: CD58
CD58
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088

2011
Entrez Id: 958
Gene Symbol: CD40
CD40
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. 22190364

2011
Entrez Id: 965
Gene Symbol: CD58
CD58
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB We also replicated several known MS associations (HLA-DR15, P = 7.0 x 10(-184); CD58, P = 9.6 x 10(-8); EVI5-RPL5, P = 2.5 x 10(-6); IL2RA, P = 7.4 x 10(-6); CLEC16A, P = 1.1 x 10(-4); IL7R, P = 1.3 x 10(-3); TYK2, P = 3.5 x 10(-3)) and observed a statistical interaction between SNPs in EVI5-RPL5 and HLA-DR15 (P = 0.001). 19525955

2009
Entrez Id: 965
Gene Symbol: CD58
CD58
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. 19525953

2009
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. 19525953

2009
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. 19525953

2009
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Replication in an independent set of 2,215 subjects with MS and 2,116 control subjects validates new MS susceptibility loci at TNFRSF1A (combined P = 1.59 x 10(-11)), IRF8 (P = 3.73 x 10(-9)) and CD6 (P = 3.79 x 10(-9)). 19525953

2009
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Risk alleles for multiple sclerosis identified by a genomewide study. 17660530

2007
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Risk alleles for multiple sclerosis identified by a genomewide study. 17660530

2007
Entrez Id: 3575
Gene Symbol: IL7R
IL7R
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.500 GeneticVariation GWASDB Risk alleles for multiple sclerosis identified by a genomewide study. 17660530

2007
Entrez Id: 23095
Gene Symbol: KIF1B
KIF1B
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.460 GeneticVariation GWASDB KIF1B is a neuronally expressed gene plausibly implicated in the irreversible axonal loss characterizing MS in the long term. 18997785

2008
Entrez Id: 868
Gene Symbol: CBLB
CBLB
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.440 GeneticVariation GWASDB Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis. 20453840

2010
Entrez Id: 3122
Gene Symbol: HLA-DRA
HLA-DRA
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.440 GeneticVariation GWASDB Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis. 20598377

2010
Entrez Id: 3122
Gene Symbol: HLA-DRA
HLA-DRA
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.440 GeneticVariation GWASDB Risk alleles for multiple sclerosis identified by a genomewide study. 17660530

2007
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.430 GeneticVariation GWASDB Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. 22190364

2011
Entrez Id: 8740
Gene Symbol: TNFSF14
TNFSF14
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.420 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088

2011
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.420 GeneticVariation GWASDB Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. 22190364

2011
Entrez Id: 923
Gene Symbol: CD6
CD6
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.420 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088

2011