Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker BEFREE MicroRNA-96 is a potential tumor repressor by inhibiting NPTX2 in renal cell carcinoma. 31498486

2020

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker BEFREE miR-96 can be considered as one of tumor-inducer and form competing endogenous RNA network with FOXO1 and DUSP1, which affects downstream EGFR signaling. 31579447

2019

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker BEFREE miR-96 acts as a tumor suppressor via targeting the BCR-ABL1 oncogene in chronic myeloid leukemia blastic transformation. 31518872

2019

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker BEFREE We also assessed the regulatory action of circPTPRA on the microRNA miR-96-5p and its target the tumor suppressor Ras association domain-containing protein 8 (RASSF8). 31160270

2019

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE The miRNAs miR-7-5p and miR-96-5p were clearly upregulated in the tumor compared to the healthy tissue. 28848144

2018

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE It was identified that miR-96-5p expression was significantly upregulated in primary HCC tumors compared with their non-tumorous counterparts. 29658604

2018

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker BEFREE microRNA-96 acts as a tumor suppressor gene in human osteosarcoma via target regulation of EZRIN. 29656060

2018

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE MEG3 overexpression resulted in miR-96 downregulation along with <i>TPM1</i> upregulation, which inhibited cell proliferation and cell cycle but promoted cell apoptosis of bladder urothelial carcinoma cells <i>in vitro</i>, and at the same time inhibited tumor growth <i>in vivo</i>. 30461333

2018

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker BEFREE In the present study, the results suggested that the introduction of miR‑96 significantly inhibited the migration and invasion, in addition to proliferation and cell cycle progression, of GBM cells and promoted their apoptosis in vitro, leading to the hypothesis that miR‑96 may be a potential tumor suppressor. 29257267

2018

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE In patients with adrenocortical tumor, serum miR-96 expression levels were significantly higher in patients with tumor diameter ≥5 cm than those with tumor diameter <5 cm (p<0.001). 30008900

2018

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE In vivo, microRNA-96 overexpression inhibits the apoptosis and increases tumor growth. 26846266

2017

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker BEFREE While anti-miR-96 transfection exhibited a tumour-suppressing function, exosomes isolated from H1299 enhanced cell viability, migration and cisplatin resistance. 28026121

2017

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE ISH analysis showed that miR-96 expression was significantly higher in the liver metastatic neoplasms compared to the primary NENs (p < 0.05); however, it was not significant for miR-133a expression levels. qRT-PCR showed that miR-96 levels were increased during progression from the primary tumors to metastases in the liver. qRT-PCR showed a decrease in miR-133a in the liver metastases compared to the primary tumors (p < 0.05). 29032398

2017

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6. 27746161

2017

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker BEFREE ANT2 shRNA downregulates miR-19a and miR-96 through the PI3K/Akt pathway and suppresses tumor growth in hepatocellular carcinoma cells. 27012708

2016

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker BEFREE Anchorage-dependent (colony formation) and anchorage-independent (tumor sphere formation) growths of these miR-96 and miR-183 expressing cells were determined. 27431799

2016

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE Overexpressing miR-96 led to increased proliferation and colony formation of normal prostate epithelial cells. miR-96 level was found to be inversely associated with the abundance of metastasis suppressor protein 1 (MTSS1) messenger RNA (mRNA), which has been proved to be a tumor suppressor for PC. 27164937

2016

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE Low miR-96-5p expression levels in tumor tissue were associated with distant metastasis (P = 0.025) and multivariate Cox regression analysis identified low levels of miR-96-5p as an independent prognostic factor with respect to cancer-specific survival (hazard ratio = 1.78, 95%CI = 1.03-3.03, P < 0.038). 25256312

2015

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE MTT assay, colony formation assay and cell cycle analysis revealed that miR-96 overexpression led to increased tumor cell viability, colony formation ability and cell cycle progression. 25369914

2015

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker BEFREE Collectively, our findings suggest that miR-96 acts as a tumor suppressor in pancreatic cancer and may therefore serve as a useful therapeutic target for the development of new anticancer therapy. 25071021

2014

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker BEFREE miR-96 promotes tumor proliferation and invasion by targeting RECK in breast cancer. 24366472

2014

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE Sixty-nine percent of the miRNAs (27/39) had tumor-associated target genes, and the expression levels of six of those (miR-126, miR-96, miR-144, miR-657, miR-490-5p, and miR-323-3p) were confirmed by quantitative (q)RT-PCR. 24641388

2014

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker BEFREE miR‑96 functions as a tumor suppressor gene by targeting NUAK1 in pancreatic cancer. 25242509

2014

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE Inhibition of miR-96 caused expression increase of tumor suppressor gene FOXO1, thus manipulating miR-96 expression may be a promising approach in treatment of prostate cancer. 24633705

2014

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression BEFREE Results revealed the upregulation of miR-96-5p (9.35-fold; p = 0.000115), miR-182-5p (7.75-fold; p = 0.000033), miR-7-5p (6.71-fold; p = 0.015626), and miR-21-5p (6.10-fold; p = 0.000000) in tumors group. 24810926

2014