×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
Biomarker
BEFREE
Here we tested the performance of the Ion Torrent PGM platform with the Ion AmpliSeq BRCA1 and BRCA2 Panel in our clinical routine of breast/ovarian hereditary cancer syndrome assessment.
31065452 2019
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
The yield of targeted genotyping for the recurring mutations in BRCA1/2 in Israel.
29086229 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
The BRCA1 c. 5096G>A p.Arg1699Gln (R1699Q) intermediate risk variant: breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium.
28490613 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Gene-panel testing of breast and ovarian cancer patients identifies a recurrent RAD51C duplication.
28802053 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations.
29446198 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
BRCA1 and BRCA2 germline variants in breast cancer patients from the Republic of Macedonia.
29335924 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Is there a genetic anticipation in breast and/or ovarian cancer families with the germline c.3481_3491del11 mutation?
28493033 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
BRCA1 and BRCA2 mutation spectrum - an update on mutation distribution in a large cancer genetics clinic in Norway.29339979 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Mutations in context: implications of BRCA testing in diverse populations.
28918466 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study.
29337092 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
Biomarker
BEFREE
Lynch syndrome and BRCA-1 and BRCA-2-associated hereditary breast and ovarian cancer are hereditary cancer syndromes frequently involving the gynaecological tract but tumours associated with similar molecular alterations may also occur sporadically.
29287922 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
BRCA1 and BRCA2 mutation spectrum - an update on mutation distribution in a large cancer genetics clinic in Norway.29339979 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Genetic and clinical characteristics in Japanese hereditary breast and ovarian cancer: first report after establishment of HBOC registration system in Japan.
29176636 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Characterization of mutations in BRCA1/2 and the relationship with clinic-pathological features of breast cancer in a hereditarily high-risk sample of chinese population.
29435039 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
High prevalence of deleterious BRCA1 and BRCA2 germline mutations in arab breast and ovarian cancer patients.
29297111 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
BRCA1 and BRCA2 mutations in ovarian cancer patients from China: ethnic-related mutations in BRCA1 associated with an increased risk of ovarian cancer.
28176296 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
"A new case of ""de novo"" BRCA1 mutation in a patient with early-onset breast cancer."
28265380 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
A case series of three Sri Lankan families with hereditary breast and ovarian cancer syndrome due to pathogenic germline mutations in the BRCA1 gene
28390335 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Clinical Variant Classification: A Comparison of Public Databases and a Commercial Testing Laboratory.
28408614 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Spectrum of genetic variants of BRCA1 and BRCA2 in a German single center study.
28324225 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Spectrum of genetic variants of BRCA1 and BRCA2 in a German single center study.
28324225 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Molecular characterization and clinical interpretation of BRCA1/BRCA2 variants in families from Murcia (south-eastern Spain) with hereditary breast and ovarian cancer: clinical-pathological features in BRCA carriers and non-carriers.
28477318 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Lost in translation: returning germline genetic results in genome-scale cancer research.
28454591 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Contribution of germline mutations in cancer predisposition genes to tumor etiology in young women diagnosed with invasive breast cancer.
28503720 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
A high frequency of PALB2 mutations in Jamaican patients with breast cancer.
28194609 2017