×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Identification of CD5/Cyclin D1 Double-negative Pleomorphic Mantle Cell Lymphoma : A Clinicopathologic, Genetic, and Gene Expression Study.
31688139
2020
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Regulation of SOX11 expression through CCND1 and STAT3 in mantle cell lymphoma .
30530749
2019
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
In conclusion, we report 3 cases of nodal PMBL, 2 of them without mediastinal mass, and expression of cyclin D1 due to copy number gains of CCND1 gene, a diagnostic pitfall with mantle cell lymphoma and DLBCL, not otherwise specified.
30211726
2019
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
When cyclin D1 was overexpressed by the Eμ-cyclin D1 transgene, ATA B cells progressed to further diffused lymphoma in aged mice, including in various lymph nodes with accumulation of IgM<sup>hi</sup>IgD<sup>lo</sup>CD5<sup>+</sup>CD23<sup>-</sup>CD43<sup>+</sup> cells, resembling aggressive human mantle cell lymphoma .
29898964
2018
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Cyclin D1 -CDK4 activity drives sensitivity to bortezomib in mantle cell lymphoma by blocking autophagy-mediated proteolysis of NOXA.
30180865
2018
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Cyclin D1 mRNA as a molecular marker for minimal residual disease monitoring in patients with mantle cell lymphoma .
29273915
2018
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
In addition, cyclin D1 overexpression sensitized cells to transcription inhibitors, revealing a synthetic lethality interaction that was also observed in primary mantle cell lymphoma cases.
29990311
2018
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Cyclin D1 depletion induces DNA damage in mantle cell lymphoma lines.
27338091
2017
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Cyclin D1 -positive tumor cells are commonly found in mantle cell lymphoma but they are very rare in diffuse large B-cell lymphoma.
28296741
2017
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Role of SOX11 and Genetic Events Cooperating with Cyclin D1 in Mantle Cell Lymphoma .
28466437
2017
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Mantle cell lymphoma with a novel t(11;12)(q13;p11.2) : a proposed alternative mechanism of CCND1 up-regulation.
28132860
2017
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Cyclin D1 protein expression in lymphocytes is classically associated with mantle cell lymphoma .
28038705
2017
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma .
27713153
2016
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
CTD_human
Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas.
26174628
2016
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Translocation t(11;14)(q13;q32) CCND1 -IGH is typically associated with mantle cell lymphoma or a subset of plasma cell myeloma and is exceedingly rare in myeloid neoplasm.
27810077
2016
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Discovery and characterization of a novel CCND1 /MRCK gene fusion in mantle cell lymphoma .
27025456
2016
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Quantitative PCR detection of t(11;14) bcl-1 /JH in mantle cell lymphoma patients: comparison of peripheral blood and bone marrow aspirate samples.
26744872
2015
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Detection of t(12;14)(p13;q32) in a patient with IGH-CCND1 negative mantle cell lymphoma resembling ultra-high risk chronic lymphocytic leukemia.
26261659
2015
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Unusual concomitant rearrangements of Cyclin D1 and MYC genes in blastoid variant of mantle cell lymphoma : Case report and review of literature.
23313364
2013
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
CCND2 rearrangements are the most frequent genetic events in cyclin D1 (-) mantle cell lymphoma .
23255553
2013
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Cyclin D1 (CCND1 ) messenger RNA expression as assessed by real-time PCR contributes to diagnosis and follow-up control in patients with mantle cell lymphoma .
24060591
2013
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Cyclin D1 -negative mantle cell lymphoma .
23429984
2013
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
The recognition of cyclin D1 expression in PC of a significant minority of CLL/SLL can be a diagnostic aid and should not lead to the diagnosis of focal mantle cell lymphoma .
22706868
2012
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Mantle cell lymphoma is a B cell malignancy in which constitutive dysregulation of cyclin D1 and the cell cycle, disruption of DNA damage response pathways, and activation of cell survival mechanisms contribute to oncogenesis.
23023712
2012
×
Entrez Id:
595
Gene Symbol:
CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Flipping the cyclin D1 switch in mantle cell lymphoma .
22687450
2012