Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.070 Biomarker BEFREE miR-3120-5p promotes colon cancer stem cell stemness and invasiveness through targeting Axin2. 29307822

2018

Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.070 Biomarker BEFREE AXIN2, an important regulator in Wnt/β-catenin signaling pathway, takes part in regulating cell proliferation, cytometaplasia, migration, apoptosis and other important functions, has showed close relations with the development of liver cancer, colon cancer, lung cancer, breast cancer and so on. 25504512

2015

Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.070 GeneticVariation BEFREE The finding was reminiscent of a previously described family harboring an AXIN2 mutation which could be shown to segregate with both the tooth agenesis and the predisposition to colon cancer transmitted in this family. 24631698

2014

Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.070 GeneticVariation BEFREE Furthermore, AXIN2, a gene that when mutated increases susceptibility to colon cancer, also is associated with CL/P. 19119171

2009

Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.070 AlteredExpression BEFREE Knock-down of conductin by small interfering RNA in colon carcinoma cells or gene ablation in mouse embryo fibroblasts enforces the checkpoint. 16815967

2006

Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.070 AlteredExpression BEFREE Regulation of axin2 expression at the levels of transcription, translation and protein stability in lung and colon cancer. 15885887

2006

Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.070 AlteredExpression BEFREE In 30 human cell lines derived from different origins, axin2 and hnkd were expressed only in human colon cancer cell lines that are known to have activating mutations in the Wnt/beta-catenin pathway. 11752446

2001