Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.550 AlteredExpression BEFREE In this study, both the mRNA and protein expression levels of LKB1, p53, and p21 decreased in OCCs following transfection with a miR-17 expression plasmid. 25510663

2015

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.550 Biomarker BEFREE Results of the present study suggested that combined therapy with eukaryotic co-expression of the plasmid‑carrying STAT3-specific siRNA and LKB1 is a novel and efficient treatment strategy for human ovarian cancer. 25420630

2015

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.550 Biomarker BEFREE Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer. 24170201

2014

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.550 Biomarker BEFREE Recent studies showed that loss of function of LKB1 is associated with sporadic forms of lung, pancreatic, and ovarian cancer. 17761947

2007

Entrez Id: 6794
Gene Symbol: STK11
STK11
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.550 GeneticVariation BEFREE Our results suggest that mutations of the STK11 gene may play a limited role in the development of ovarian carcinomas. 10429654

1999